Simple Summary This study pursued the proteomic analysis of primary uveal melanoma
(pUM) for insights into the mechanisms of metastasis and protein biomarkers. Liquid …

Uveal melanoma (UM) continues to be associated with a high mortality rate of up to 50%
due to metastatic spread primarily to the liver. Currently there are relatively effective …

Background Uveal melanoma is the most common malignancy of the adult eye. The overall
mortality rate is high because this aggressive cancer often metastasizes before ophthalmic …

purpose. Patient survival in uveal melanoma may benefit from earlier recognition of potential
metastases to the liver, but as yet, proper markers indicating metastases are not available …

Uveal melanoma is the most common primary intraocular malignancy in adults, with an
incidence of 5–7 per million per year. It is associated with the development of metastasis in …

Purpose: To determine the association between gene-expression profiling (GEP), next-
generation sequencing (NGS), preferentially expressed antigen in melanoma (PRAME) …

Objectives Uveal melanoma (UM) is the most common primary intraocular malignancy in
adults, and immune infiltration plays a crucial role in the prognosis of UM. This study aimed …

Uveal melanoma (UM) is the most frequent primary intraocular tumor in adult humans.
Despite the significant advances in diagnosis and treatment of UM in the last decades, the …

Proteomics in uveal melanoma : Current Opinion in Ophthalmology Proteomics in uveal
melanoma : Current Opinion in Ophthalmology Log in or Register Subscribe to journalSubscribe …

Background: Metastasis is a major cause of death in UM, highlighting the need to use highly
specific and sensitive prognostic markers to identify patients with a risk of developing …