The microtubule (MT) cytoskeleton supports a broad range of cellular functions, from
providing tracks for intracellular transport, to supporting movement of cilia and flagella, to …

The fact that some kinesin-related proteins can destabilize microtubules is now a well-
established fact. However, the contribution that these kinesins make to cellular function is …

The simple mechanistic and functional division of the kinesin family into either active
translocators or non-motile microtubule depolymerases was initially appropriate but is now …

The kinesin-13 class of motors catalyses microtubule depolymerisation by bending tubulins
at microtubule ends. Depolymerisation activity is intrinsic to the kinesin-13 motor core but the …

Microtubules are critical for a variety of important functions in eukaryotic cells. During
intracellular trafficking, molecular motor proteins of the kinesin superfamily drive the …

The interplay between microtubules and microtubule-based motors is fundamental to basic
aspects of cellular function, such as the intracellular transport of organelles and alterations …

Microtubule‐based motor proteins play key roles during mitosis to assemble the bipolar
spindle, define the cell division axis, and align and segregate the chromosomes. The …

The stereotypical function of kinesin superfamily motors is to transport cargo along
microtubules. However, some kinesins also shape the microtubule track by regulating …

Kinesins are motor proteins that use the hydrolysis of ATP to do mechanical work. Most of
these motors translocate cargo along the surface of the microtubule (MT). However, a …

Proteins from the kinesin-8 family promote microtubule (MT) depolymerization, a process
thought to be important for the control of microtubule length in living cells. In addition to this …