D Klarin, E Busenkell, R Judy, J Lynch, M Levin… - Nature …, 2019 - nature.com
Venous thromboembolism is a significant cause of mortality, yet its genetic determinants are incompletely defined. We performed a discovery genome-wide association study in the …
M Crous-Bou, LB Harrington… - Seminars in thrombosis …, 2016 - thieme-connect.com
Venous thromboembolism (VTE) includes deep vein thrombosis and pulmonary embolism, and a combination of environmental and genetic risk factors contributes to VTE risk. Within …
Background Venous Thrombosis (VT) is a common multifactorial disease associated with a major public health burden. Genetics factors are known to contribute to the susceptibility of …
R Gohil, G Peck, P Sharma - Thrombosis and haemostasis, 2009 - thieme-connect.com
We conducted a systematic and comprehensive meta-analysis on all candidate genes to assess their genetic contribution to the aetiology of venous thromboembolism …
PE Morange, P Suchon… - Thrombosis and …, 2015 - thieme-connect.com
Venous thrombosis (VT) is a common multifactorial disease with a genetic component that was first suspected nearly 60 years ago. In this review, we document the genetic …
We report a genome-wide association study of venous thromboembolism (VTE) incorporating 81,190 cases and 1,419,671 controls sampled from six cohorts. We identify 93 …
Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality. To advance our understanding of the biology contributing to VTE, we conducted a genome …
PE Morange, DA Trégouët - Journal of thrombosis and …, 2013 - Wiley Online Library
The genetic burden underlying venous thrombosis (VT) is characterized by a sibling relative risk of 2.5 and a strong heritability whose estimates varied from 35% to 60% according to …
JA Heit, SM Armasu, YW Asmann… - Journal of thrombosis …, 2012 - Elsevier
Objectives: To identify venous thromboembolism (VTE) disease‐susceptibility genes. Patients and methods: We performed in silico genome wide association scan (GWAS) …