Remarkable progress has been made during the last 2 decades in understanding telomere
biology at the molecular and cellular levels. Clinical epidemiology research of human …

Telomere length is an important parameter of telomere function since it determines number
of aspects controlling chromosome stability and cell division. Since telomeres shorten with …

Telomeres are the tips of chromosomes and consist of proteins and hexanucleotide tandem
repeats of DNA. The DNA repeats are shortened at each mitotic division of normal cells, and …

The International Journal of Epidemiology continues to be an important forum for
discussions of both methodological1–7 and theoretical8, 9 issues in telomere epidemiology …

Telomerase is perceived as an immortality enzyme that might provide longevity to cells and
whole organisms. Importantly, it is generally inactive in most somatic cells of healthy, adult …

There are neglected but growing problems in the epidemiological field of telomere biology.
The focus of the field has been on leukocyte telomere dynamics, which ostensibly register …

The Nobel Prize in Physiology or Medicine 2009 was recently awarded to three scientists for
their work on telomeres, which are repetitive DNA structures at the tips of chromosomes, and …

The importance of telomere biology in human disease is increasingly recognized and, in
parallel, use of telomere length (TL) measures is proliferating in epidemiological and clinical …

Telomeres, the repetitive sequences that protect the ends of chromosomes, help to maintain
genomic integrity and are of key importance to human health. The aim here is to give an …

The ends of human chromosomes are constituted of telomeres, a nucleoprotein complex.
They are mainly formed by the entanglement of repeat DNA and telomeric and non …