Catalyst-Free Construction of Versatile and Functional CS2-Based Polythioureas: Characteristics from Self-Healing to Heavy Metal Absorption

S Wu, M Luo, DJ Darensbourg, X Zuo - Macromolecules, 2019 - ACS Publications
As typical of sulfur-containing polymers, polythiourea is a promising polymeric material
because of its outstanding properties such as self-healing, high refractive index, high …

On-demand therapeutic delivery of hydrogen sulfide aided by biomolecules

Y Ge, F Rong, W Li, Y Wang - Journal of Controlled Release, 2022 - Elsevier
Abstract Hydrogen sulfide (H 2 S), known as the third gasotransmitter, exerts various
physiological functions including cardiac protection, angiogenesis, anti-inflammatory, and …

Polyprodrug with glutathione depletion and cascade drug activation for multi-drug resistance reversal

X Xiao, K Wang, Q Zong, Y Tu, Y Dong, Y Yuan - Biomaterials, 2021 - Elsevier
High intracellular glutathione (GSH) levels play an important role in multidrug resistance
(MDR) in cancer cells. It remains challenging to develop a drug delivery system that is …

Bioconjugation using thiols: old chemistry rediscovered to connect polymers with nature's building blocks

MH Stenzel - 2013 - ACS Publications
Various pathways to bioconjugates based on thiol chemistry are discussed. Thiol-halogeno,
thiol-parafluoro, thiol-ene, thiol-yne, thiol-vinylsulfone and thiol–vinyl sulfone, thiol …

Harnessing strained disulfides for photocurable adaptable hydrogels

GM Scheutz, JL Rowell, ST Ellison, JB Garrison… - …, 2020 - ACS Publications
We report a photomediated disulfide cross-linking strategy for the generation of adaptable
hydrogels from telechelic network precursors containing strained cyclic disulfides. Exploiting …

Synthesis of (Bio)‐Degradable Poly(β‐thioester)s via Amine Catalyzed Thiol−Ene Click Polymerization

J Vandenbergh, K Ranieri… - … Chemistry and Physics, 2012 - Wiley Online Library
The well‐known thiol‐ene click reaction is used to polymerize dithiols and diacrylate
monomers. Using catalytic amounts of hexylamine, poly (ester‐sulfide) s are synthesized via …

Hydrophobic cysteine poly (disulfide)‐based redox‐hypersensitive nanoparticle platform for cancer theranostics

J Wu, L Zhao, X Xu, N Bertrand, WII Choi… - Angewandte …, 2015 - Wiley Online Library
Selective tumor targeting and drug delivery are critical for cancer treatment. Stimulus‐
sensitive nanoparticle (NP) systems have been designed to specifically respond to …

Intracellular drug delivery nanocarriers of glutathione-responsive degradable block copolymers having pendant disulfide linkages

B Khorsand, G Lapointe, C Brett, JK Oh - Biomacromolecules, 2013 - ACS Publications
Self-assembled micelles of amphiphilic block copolymers (ABPs) with stimuli-responsive
degradation (SRD) properties have a great promise as nanotherapeutics exhibiting …

Engineering reversible hydrogels for 3D cell culture and release using diselenide catalyzed fast disulfide formation

Y Han, C Liu, H Xu, Y Cao - Chinese Journal of Chemistry, 2022 - Wiley Online Library
Comprehensive Summary Hydrogels crosslinked by dynamic covalent bonds can effectively
mimic the viscoelastic properties of native extracellular matrix and have been widely …

The link to polysulfides and their applications

KW Park, EM Leitao - Chemical Communications, 2021 - pubs.rsc.org
This article highlights recent discoveries within the field of polysulfides which are created
from waste sulfur through inverse vulcanisation. Due to the current environmental climate …