Renal damage in primary aldosteronism: a systematic review and meta-analysis

S Monticone, E Sconfienza, F D'Ascenzo… - Journal of …, 2020 - journals.lww.com
Objectives: In experimental animal models, exogenous aldosterone excess has been linked
to the progression of renal disease. However, the evidence of an increased risk of renal …

Predictors of decreasing glomerular filtration rate and prevalence of chronic kidney disease after treatment of primary aldosteronism: renal outcome of 213 cases

Y Iwakura, R Morimoto, M Kudo, Y Ono… - The Journal of …, 2014 - academic.oup.com
Context: In primary aldosteronism (PA), glomerular hyperfiltration due to excessive
aldosterone is considered to underestimate actual renal damage. Objective: Our objectives …

Risk factors associated with a low glomerular filtration rate in primary aldosteronism

M Reincke, LC Rump, M Quinkler… - The Journal of …, 2009 - academic.oup.com
Context: Primary aldosteronism (PA) is associated with vascular end organ damage.
Objective: We evaluated the newly established German Conn's Registry for evidence of …

Effectiveness of eplerenone or spironolactone treatment in preserving renal function in primary aldosteronism

V Fourkiotis, O Vonend, S Diederich… - European journal of …, 2013 - academic.oup.com
Objective Primary aldosteronism (PA) has deleterious effects on kidney function
independent of blood pressure levels. Up to now, data on effectiveness of different PA …

Higher risk of chronic kidney disease and progressive kidney function impairment in primary aldosteronism than in essential hypertension. Case-control study

M Fernández-Argüeso, E Pascual-Corrales… - Endocrine, 2021 - Springer
Purpose To study the differences in the prevalence, risk, and grade of control of different
cardiometabolic comorbidities in patients with primary aldosteronism (PA) and essential …

Comorbidities in primary aldosteronism

M Quinkler, E Born-Frontsberg… - Hormone and …, 2010 - thieme-connect.com
Patients presenting with primary aldosteronism experience more cardiovascular events than
patients with essential hypertension independent of blood pressure. Therefore, the presence …

Cardiovascular risk in primary hyperaldosteronism

A Prejbisz, E Warchoł-Celińska… - Hormone and …, 2015 - thieme-connect.com
After the first cases of primary aldosteronism were described and characterized by Conn, a
substantial body of experimental and clinical evidence about the long-term effects of excess …

Long-term renal outcomes in patients with primary aldosteronism

LA Sechi, M Novello, R Lapenna, S Baroselli… - Jama, 2006 - jamanetwork.com
ContextExperimental animal studies indicate that exposure to increased aldosterone levels
might result in renal damage, but the clinical evidence supporting this role of aldosterone is …

Renal impairment is closely associated with plasma aldosterone concentration in patients with primary aldosteronism

A Kawashima, M Sone, N Inagaki… - European Journal of …, 2019 - academic.oup.com
Objective Several clinical studies have reported that renal impairments are sometimes
observed in patients with primary aldosteronism (PA). We analyzed the prevalence of renal …

Kidney impairment in primary aldosteronism

VC Wu, SY Yang, JW Lin, BW Cheng, CC Kuo… - Clinica Chimica …, 2011 - Elsevier
Background Kidney impairment is noted in primary aldosteronism (PA), and probably
initiated by glomerular hyperfiltration. Methods A prospectively defined survey was …