The blood–brain barrier (BBB) plays a vital role in maintaining the specialized
microenvironment of the neural tissue. It separates the peripheral circulatory system from the …

The blood–brain barrier (BBB) plays a vital role in maintaining the specialized
microenvironment of the brain tissue. It facilitates communication while separating the …

Vascular dysfunction is frequently observed in disorders associated with cognitive
impairment, dementia and Alzheimer's disease (AD). Recent advances in neuroimaging and …

The blood–brain barrier (BBB) is a continuous endothelial membrane within brain
microvessels that has sealed cell-to-cell contacts and is sheathed by mural vascular cells …

Objective Blood–brain barrier (BBB) breakdown has been suggested to be an early
biomarker in human cognitive impairment. However, the relationship between BBB …

The current pathogenic scenarios of different types of dementia are based on a number of
common mechanisms of neurodegeneration, such as accumulation of abnormal proteins …

The aging process correlates with a progressive failure in the normal cellular and organ
functioning; these alterations are aggravated in Alzheimer's disease (AD). In both aging and …

The existence of a selective blood-brain barrier (BBB) and neurovascular coupling are two
unique central nervous system vasculature features that result in an intimate relationship …

Introduction Blood‐brain barrier (BBB) breakdown is observed in older versus younger
adults and in late‐onset Alzheimer's disease versus age‐matched controls, but its causes …

Blood–brain barrier (BBB) breakdown can disrupt nutrient supply and waste removal, which
affects neuronal functioning. Currently, dynamic contrast-enhanced (DCE) MRI is the …