[HTML][HTML] Cytokine profile in plasma of severe COVID-19 does not differ from ARDS and sepsis

JG Wilson, LJ Simpson, AM Ferreira, A Rustagi… - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND Elevated levels of inflammatory cytokines have been associated with poor
outcomes among COVID-19 patients. It is unknown, however, how these levels compare …

Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

H Han, Q Ma, C Li, R Liu, L Zhao, W Wang… - Emerging microbes & …, 2020 - Taylor & Francis
Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly
spread across many other countries. While the majority of patients were considered mild …

[HTML][HTML] Clinical and pathological investigation of patients with severe COVID-19

S Li, L Jiang, X Li, F Lin, Y Wang, B Li, T Jiang, W An… - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND. Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
coronavirus 2 (SARS-CoV-2), has become a pandemic. This study addresses the clinical …

Cytokines and their relationship with the severity and prognosis of coronavirus disease 2019 (COVID-19): a retrospective cohort study

QQ Liu, A Cheng, Y Wang, H Li, L Hu, X Zhao… - BMJ open, 2020 - bmjopen.bmj.com
Objective To delineate the characteristics and clinical significance of plasma inflammatory
cytokines altered in COVID-19. Design Retrospective, single-centre cohort study. Setting …

Distinct cytokine profiles associated with COVID-19 severity and mortality

K Dorgham, P Quentric, M Gökkaya, S Marot… - Journal of Allergy and …, 2021 - Elsevier
Background Markedly elevated levels of proinflammatory cytokines and defective type-I
interferon responses were reported in patients with coronavirus disease 2019 (COVID-19) …

[HTML][HTML] Dynamic changes in serum IL-6, IL-8, and IL-10 are associated with the outcome of patients with severe COVID-19 in ICU

J Li, L Rong, R Cui, J Feng, Y Jin, Y Yu, X Chen, R Xu - 2020 - europepmc.org
Background: Biomarkers that would help prognosticate outcomes and guide treatment of
patients with severe coronavirus disease 2019 (COVID-19) are currently required. We aimed …

[HTML][HTML] Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease

Y Zhao, L Qin, P Zhang, K Li, L Liang, J Sun, B Xu… - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND. Identifying immune correlates of COVID-19 disease severity is an urgent
need for clinical management, vaccine evaluation, and drug development. Here, we present …

Immunity and inflammatory biomarkers in COVID‐19: a systematic review

APD Iwamura, MR Tavares da Silva… - Reviews in Medical …, 2021 - Wiley Online Library
Summary Coronavirus disease 2019 (COVID‐19) is a clinical syndrome caused by the
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) virus. Patients can be …

[HTML][HTML] Pro-and anti-inflammatory responses in severe COVID-19-induced acute respiratory distress syndrome—an observational pilot study

Q Notz, M Schmalzing, F Wedekink… - Frontiers in …, 2020 - frontiersin.org
Objectives The severity of Coronavirus Disease 2019 (COVID-19) is largely determined by
the immune response. First studies indicate altered lymphocyte counts and function …

[HTML][HTML] Clinical utility of inflammatory biomarkers in COVID-19 in direct comparison to other respiratory infections—A prospective cohort study

M Lampart, N Zellweger, S Bassetti, S Tschudin-Sutter… - PloS one, 2022 - journals.plos.org
Background Inflammatory biomarkers are associated with severity of coronavirus disease
2019 (COVID-19). However, direct comparisons of their utility in COVID-19 versus other …