[HTML][HTML] KLF3 transcription activates WNT1 and promotes the growth and metastasis of gastric cancer via activation of the WNT/β-Catenin signaling pathway

Y Li, Y Wang, Q Zou, S Li, F Zhang - Laboratory Investigation, 2023 - Elsevier
The transcription factor Krüppel-like factor (KLF) 3 is one of the members of the KLF family,
which plays an important role in tumor progression. Nevertheless, the role of KLF3 in the …

Krüppel-like factor 4 negatively regulates β-catenin expression and inhibits the proliferation, invasion and metastasis of gastric cancer

N Zhang, J Zhang, L Shuai, L Zha… - International …, 2012 - spandidos-publications.com
Krüppel-like factor 4 (KLF4) is a zinc-finger protein that plays an important role in the
progression of gastric carcinoma. The abnormal activation of β-catenin frequently occurs in …

[HTML][HTML] KLF16 promotes proliferation in gastric cancer cells via regulating p21 and CDK4

P Ma, CQ Sun, YF Wang, YT Pan… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Krüppel-like factors (KLFs), such as KLF4, KLF2, KLF5 and KLF15, have been extensively
investigated in multi-cancers. However, KLF16, a member of KLFs, hasn't been well …

[PDF][PDF] KLF5 promotes proliferation in gastric cancer via regulating p21 and CDK4.

P Chen, XK Qian, YF Zhang, XG Sun… - European Review for …, 2020 - europeanreview.org
OBJECTIVE: This study aims to investigate the expression characteristics of Krüppel-like
factor 5 (KLF5) in gastric cancer (GC) and its potential correlation to pathological indexes in …

[HTML][HTML] A novel mechanism driving poor-prognostic gastric cancer: overexpression of the transcription factor Krüppel-like factor 16 promotes growth and metastasis of …

DP Sun, YF Tian, CC Lin, ST Hung… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Gastric cancer (GC) is one of the most common malignant tumors worldwide and has high
rates of morbidity and mortality. This study investigated the role of Krüppel-like factor 16 …

KLF8 involves in TGF-beta-induced EMT and promotes invasion and migration in gastric cancer cells

H Zhang, L Liu, Y Wang, G Zhao, R Xie, C Liu… - Journal of cancer …, 2013 - Springer
Purpose Krüppel-like factor 8 (KLF8), a downstream transcription factor of transforming
growth factor-β1 (TGF-β1), has a role in tumorigenesis, tumor progress and epithelial-to …

KLF8 is associated with poor prognosis and regulates glycolysis by targeting GLUT4 in gastric cancer

A Mao, X Zhou, Y Liu, J Ding, A Miao… - Journal of cellular and …, 2019 - Wiley Online Library
Krüppel‐like transcription factor (KLF) family is involved in tumorigenesis in different types of
cancer. However, the importance of KLF family in gastric cancer is unclear. Here, we …

[HTML][HTML] Krüppel-like factor 7 is a marker of aggressive gastric cancer and poor prognosis

Z Jiang, T Yu, Z Fan, H Yang, X Lin - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Krüppel-like factor (KLF) 7 protein is a member of the KLF transcription
factor family, which plays important roles in regulating the expression of genes involved in …

[HTML][HTML] Krüppel-like factor 2 suppresses human gastric tumorigenesis through inhibiting PTEN/AKT signaling

C Wang, L Li, Q Duan, Q Wang, J Chen - Oncotarget, 2017 - ncbi.nlm.nih.gov
Krüppel-like factors (KLFs) are a large family of DNA-binding transcriptional regulators that
affect basic cellular processes such as growth, survival, migration and differentiation and …

Regulation of EMT by KLF4 in gastrointestinal cancer

J Cui, M Shi, M Quan, K Xie - Current cancer drug targets, 2013 - ingentaconnect.com
Gastrointestinal (GI) cancer is characterized by its aggressiveness, but the underlying
mechanism is not fully understood. Studies reveal that epithelial to mesenchymal transition …