Rapid development of effective vaccines against SARS-CoV-2 has been a major
achievement in the global effort of controlling the COVID-19 pandemic [1-5]. However, the …

The current study aims to develop a safe and highly immunogenic COVID-19 vaccine. The
novel combination of a DNA vaccine encoding the full-length Spike (S) protein of SARS-CoV …

Aim: This study aimed to develop a universal vaccine that can effectively address future
outbreaks of coronavirus infections. Materials & methods: We developed recombinant DNA …

Nucleic acid vaccines are designed based on genetic sequences (DNA or mRNA) of a target
antigen to be expressed in vivo to drive a host immune response. In response to the COVID …

Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), initially
originated in China in year 2019 and spread rapidly across the globe within 5 months …

ABSTRACT Introduction: Coronavirus outbreak 2019 (COVID-19) has affected all the
corners of the globe and created chaos to human life. In order to put some control on the …

Objective: We constructed two DNA vaccines containing the receptor-binding domain (RBD)
genes of multiple SARS-CoV-2 variants and used them in combination with inactivated …

Several vaccines for coronavirus disease 2019 have been developed worldwide. A
heterologous prime-boost strategy has been identified as a potential method for achieving …

Integrating different types of vaccines into a singular immunization regimen is an effective
and accessible approach to strengthen and broaden the immunogenicity of existing …

To overcome the COVID-19 pandemic, the development of safe and effective vaccines is
crucial. With the enormous information available on vaccine development for COVID-19 …