Heightened innate immune responses in the respiratory tract of COVID-19 patients
The outbreaks of 2019 novel coronavirus disease (COVID-19) caused by SARS-CoV-2
infection have posed a severe threat to global public health. It is unclear how the human …
infection have posed a severe threat to global public health. It is unclear how the human …
Circulating extracellular particles from severe COVID-19 patients show altered profiling and innate lymphoid cell-modulating ability
Introduction Extracellular vesicles (EVs) and particles (EPs) represent reliable biomarkers
for disease detection. Their role in the inflammatory microenvironment of severe COVID-19 …
for disease detection. Their role in the inflammatory microenvironment of severe COVID-19 …
The interplay between the airway epithelium and tissue macrophages during the SARS-CoV-2 infection
E Barreto-Duran, A Szczepański… - Frontiers in …, 2022 - frontiersin.org
The first line of antiviral immune response in the lungs is secured by the innate immunity.
Several cell types take part in this process, but airway macrophages (AMs) are among the …
Several cell types take part in this process, but airway macrophages (AMs) are among the …
Innate lymphoid cells (ILC) in SARS-CoV-2 infection
A Kumar, W Cao, K Endrias, SV Kuchipudi… - Molecular Aspects of …, 2021 - Elsevier
Abstract Innate Lymphoid Cells (ILCs) are a class of innate immune cells that form the first
line of defense against internal or external abiotic and biotic challenges in the mammalian …
line of defense against internal or external abiotic and biotic challenges in the mammalian …
TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS‐CoV‐2 infection
RM van der Sluis, LB Cham, A Gris‐Oliver… - The EMBO …, 2022 - embopress.org
Understanding the molecular pathways driving the acute antiviral and inflammatory
response to SARS‐CoV‐2 infection is critical for developing treatments for severe COVID …
response to SARS‐CoV‐2 infection is critical for developing treatments for severe COVID …
SARS-CoV-2 productively infects primary human immune system cells in vitro and in COVID-19 patients
MC Pontelli, ÍA Castro, RB Martins… - Journal of Molecular …, 2022 - academic.oup.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated
with a hyperinflammatory state and lymphocytopenia, a hallmark that appears as both …
with a hyperinflammatory state and lymphocytopenia, a hallmark that appears as both …
Neutrophils in COVID-19: recent insights and advances
J Li, K Zhang, ye Zhang, Z Gu, C Huang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to acute …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to acute …
Plasmacytoid dendritic cells produce type I interferon and reduce viral replication in airway epithelial cells after SARS-CoV-2 infection
L Cervantes-Barragan, A Vanderheiden, CJ Royer… - bioRxiv, 2021 - biorxiv.org
Infection with SARS-CoV-2 has caused a pandemic of unprecedented dimensions. SARS-
CoV-2 infects airway and lung cells causing viral pneumonia. The importance of type I …
CoV-2 infects airway and lung cells causing viral pneumonia. The importance of type I …
Direct comparison of different therapeutic cell types susceptibility to inflammatory cytokines associated with COVID-19 acute lung injury
Background Although 90% of infections with the novel coronavirus 2 (COVID-19) are mild,
many patients progress to acute respiratory distress syndrome (ARDS) which carries a high …
many patients progress to acute respiratory distress syndrome (ARDS) which carries a high …
A missing link: engagements of dendritic cells in the pathogenesis of SARS-CoV-2 infections
A Alamri, D Fisk, D Upreti, SKP Kung - International Journal of Molecular …, 2021 - mdpi.com
Dendritic cells (DC) connect the innate and adaptive arms of the immune system and carry
out numerous roles that are significant in the context of viral disease. Their functions include …
out numerous roles that are significant in the context of viral disease. Their functions include …