The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV

N Hemmat, Z Asadzadeh, NK Ahangar… - Archives of …, 2021 - Springer
The number of descriptions of emerging viruses has grown at an unprecedented rate since
the beginning of the 21 st century. Severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …

Inflammatory pathways in COVID‐19: mechanism and therapeutic interventions

Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

Dysregulation of cell signaling by SARS-CoV-2

RK Suryawanshi, R Koganti, A Agelidis, CD Patil… - Trends in …, 2021 - cell.com
Pathogens usurp host pathways to generate a permissive environment for their propagation.
The current spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …

SARS‐CoV‐2: Mechanism of infection and emerging technologies for future prospects

S Li, S Li, C Disoma, R Zheng, M Zhou… - Reviews in Medical …, 2021 - Wiley Online Library
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has
spread globally to over 200 countries with more than 23 million confirmed cases and at least …

[HTML][HTML] SARS-CoV-2 pathophysiology and assessment of coronaviruses in CNS diseases with a focus on therapeutic targets

J Vallamkondu, A John, WY Wani, SP Ramadevi… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The novel Coronavirus disease of 2019 (nCOV-19) is a viral outbreak noted first in Wuhan,
China. This disease is caused by Severe Acute Respiratory Syndrome (SARS) Coronavirus …

The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options

S Choudhary, K Sharma, O Silakari - Microbial pathogenesis, 2021 - Elsevier
Abstract COVID-19, caused by SARS-CoV-2, emerged as the deadliest outbreak that has
now become a serious health issue to mankind. Activation of inflammatory signaling …

Pathophysiology and treatment strategies for COVID-19

M Kumar, S Al Khodor - Journal of translational medicine, 2020 - Springer
The outbreak of Coronavirus disease of 2019 (COVID-19) caused by the Severe Acute
Respiratory Syndrome coronavirus 2 (SARS-CoV-2), has posed a serious health threat. The …

SARS-CoV-2 and the host-immune response

DP Maison, Y Deng, M Gerschenson - Frontiers in Immunology, 2023 - frontiersin.org
The SARS-CoV-2 pandemic and the COVID-19 disease have affected everyone globally,
leading to one of recorded history's most significant research surges. As our knowledge …

[HTML][HTML] COVID-19 signalome: Pathways for SARS-CoV-2 infection and impact on COVID-19 associated comorbidity

K Lundstrom, A Hromić-Jahjefendić, E Bilajac… - Cellular …, 2023 - Elsevier
The COVID-19 pandemic has been the focus of research the past two years. The major
breakthrough was made by discovering pathways related to SARS-CoV-2 infection through …