The dichotomous and incomplete adaptive immunity in COVID-19 patients with different disease severity

L Gao, J Zhou, S Yang, L Wang, X Chen… - Signal transduction and …, 2021 - nature.com
The adaptive immunity that protects patients from coronavirus disease 2019 (COVID-19),
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is not well …

Humoral immune responses in COVID-19 patients: a window on the state of the art

G Siracusano, C Pastori, L Lopalco - Frontiers in immunology, 2020 - frontiersin.org
The novel SARS-CoV-2 is a recently emerging virus causing a human pandemic. A great
variety of symptoms associated with COVID-19 disease, ranging from mild to severe …

Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals

F Zhang, R Gan, Z Zhen, X Hu, X Li, F Zhou… - Signal transduction and …, 2020 - nature.com
The global Coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has
affected more than eight million people. There is an urgent need to investigate how the …

Cellular and humoral immune responses in covid-19 and immunotherapeutic approaches

A Hasan, E Al-Ozairi, Z Al-Baqsumi… - ImmunoTargets and …, 2021 - Taylor & Francis
Abstract Coronavirus disease 2019 (Covid-19), caused by the novel coronavirus severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can range in severity from …

Innate and adaptive immune response in SARS-CoV-2 infection-Current perspectives

Q Zhu, Y Xu, T Wang, F Xie - Frontiers in Immunology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) has been a global pandemic, caused by a novel
coronavirus strain with strong infectivity, severe acute respiratory syndrome coronavirus 2 …

Updated insights into the T cell-mediated immune response against SARS-CoV-2: a step towards efficient and reliable vaccines

M Dhawan, AA Rabaan, MMA Fawarah, SA Almuthree… - Vaccines, 2023 - mdpi.com
The emergence of novel variants of SARS-CoV-2 and their abilities to evade the immune
response elicited through presently available vaccination makes it essential to recognize the …

Longitudinal dynamics of SARS-CoV-2-specific cellular and humoral immunity after natural infection or BNT162b2 vaccination

P Almendro-Vázquez, R Laguna-Goya… - PLoS …, 2021 - journals.plos.org
The timing of the development of specific adaptive immunity after natural SARS-CoV-2
infection, and its relevance in clinical outcome, has not been characterized in depth …

Persistence of SARS-CoV-2-specific B and T cell responses in convalescent COVID-19 patients 6–8 months after the infection

N Sherina, A Piralla, L Du, H Wan, M Kumagai-Braesch… - Med, 2021 - cell.com
Background Monitoring the adaptive immune responses during the natural course of severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection provides useful …

SARS-CoV-2 elicits robust adaptive immune responses regardless of disease severity

SSF Nielsen, LK Vibholm, I Monrad, R Olesen… - …, 2021 - thelancet.com
Abstract Background The SARS-CoV-2 pandemic currently prevails worldwide. To
understand the immunological signature of SARS-CoV-2 infections and aid the search and …

Longitudinal tracking of immune responses in COVID-19 convalescents reveals absence of neutralization activity against omicron and staggered impairment to other …

I Odak, CR Schultze-Florey… - Frontiers in …, 2022 - frontiersin.org
Evaluating long-term protection against SARS-CoV-2 variants of concern in convalescing
individuals is of high clinical relevance. In this prospective study of a cohort of 46 SARS-CoV …