Characteristics of Japanese inflammatory bowel disease susceptibility loci

Y Arimura, H Isshiki, K Onodera, K Nagaishi… - Journal of …, 2014 - Springer
Background There are substantial differences in inflammatory bowel disease (IBD) genetics
depending on the populations examined. We aimed to identify Japanese population-specific …

[HTML][HTML] Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease

S Hu, WT Uniken Venema, HJ Westra… - Nature …, 2021 - nature.com
More than 240 genetic risk loci have been associated with inflammatory bowel disease
(IBD), but little is known about how they contribute to disease development in involved …

[HTML][HTML] Evaluation of 22 genetic variants with Crohn's disease risk in the Ashkenazi Jewish population: a case-control study

I Peter, AA Mitchell, L Ozelius, M Erazo, J Hu… - BMC medical …, 2011 - Springer
Background Crohn's disease (CD) has the highest prevalence among individuals of
Ashkenazi Jewish (AJ) descent compared to non-Jewish Caucasian populations (NJ). We …

Using a genome-wide scan and meta-analysis to identify a novel IBD locus and confirm previously identified IBD loci

CN Williams, K Kocher, ES Lander… - Inflammatory bowel …, 2002 - academic.oup.com
Seven loci that potentially confer susceptibility to inflammatory bowel disease (IBD) or one of
its subtypes have been identified to date; however, most are unconfirmed, and the complete …

Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis

J Umeno, K Asano, T Matsushita… - Inflammatory bowel …, 2011 - academic.oup.com
Background Both ulcerative colitis (UC) and Crohn's disease (CD) have a complex etiology
involving multiple genetic and environmental factors. Many genome-wide association …

Genetics of inflammatory bowel disease in Asia: systematic review and meta-analysis

SC Ng, KKF Tsoi, MA Kamm, B Xia, J Wu… - Inflammatory bowel …, 2012 - academic.oup.com
Background Inflammatory bowel diseases (IBD) result from an interaction between genetic
and environmental factors. Preliminary findings suggest that susceptibility genes differ …

Blood and intestine eQTLs from an anti-TNF-resistant Crohn's disease cohort inform IBD genetic association loci

AF Di Narzo, LA Peters, C Argmann… - Clinical and …, 2016 - journals.lww.com
OBJECTIVES: Genome-wide association studies (GWAS) have identified loci reproducibly
associated with inflammatory bowel disease (IBD) and other immune-mediated diseases; …

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

CA Anderson, G Boucher, CW Lees, A Franke… - Nature …, 2011 - nature.com
Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis …

[HTML][HTML] Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across …

SK Yang, M Hong, W Zhao, Y Jung, J Baek, N Tayebi… - Gut, 2014 - gut.bmj.com
Objective Crohn9s disease (CD) is an intractable inflammatory bowel disease (IBD) of
unknown cause. Recent meta-analysis of the genome-wide association studies (GWAS) and …

Immunochip meta-analysis of inflammatory bowel disease identifies three novel loci and four novel associations in previously reported loci

M Hong, BD Ye, SK Yang, S Jung… - Journal of Crohn's …, 2018 - academic.oup.com
Abstract Background and Aims Recent meta-analysis of genome-wide association studies
have identified over 241 inflammatory bowel disease susceptibility loci. However, the known …