More than 240 genetic risk loci have been associated with inflammatory bowel disease (IBD), but little is known about how they contribute to disease development in involved …
I Peter, AA Mitchell, L Ozelius, M Erazo, J Hu… - BMC medical …, 2011 - Springer
Background Crohn's disease (CD) has the highest prevalence among individuals of Ashkenazi Jewish (AJ) descent compared to non-Jewish Caucasian populations (NJ). We …
CN Williams, K Kocher, ES Lander… - Inflammatory bowel …, 2002 - academic.oup.com
Seven loci that potentially confer susceptibility to inflammatory bowel disease (IBD) or one of its subtypes have been identified to date; however, most are unconfirmed, and the complete …
J Umeno, K Asano, T Matsushita… - Inflammatory bowel …, 2011 - academic.oup.com
Background Both ulcerative colitis (UC) and Crohn's disease (CD) have a complex etiology involving multiple genetic and environmental factors. Many genome-wide association …
Background Inflammatory bowel diseases (IBD) result from an interaction between genetic and environmental factors. Preliminary findings suggest that susceptibility genes differ …
AF Di Narzo, LA Peters, C Argmann… - Clinical and …, 2016 - journals.lww.com
OBJECTIVES: Genome-wide association studies (GWAS) have identified loci reproducibly associated with inflammatory bowel disease (IBD) and other immune-mediated diseases; …
Genome-wide association studies and candidate gene studies in ulcerative colitis have identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis …
SK Yang, M Hong, W Zhao, Y Jung, J Baek, N Tayebi… - Gut, 2014 - gut.bmj.com
Objective Crohn9s disease (CD) is an intractable inflammatory bowel disease (IBD) of unknown cause. Recent meta-analysis of the genome-wide association studies (GWAS) and …
M Hong, BD Ye, SK Yang, S Jung… - Journal of Crohn's …, 2018 - academic.oup.com
Abstract Background and Aims Recent meta-analysis of genome-wide association studies have identified over 241 inflammatory bowel disease susceptibility loci. However, the known …