Fitness costs of plasmids: a limit to plasmid transmission

A San Millan, RC MacLean - Microbiology spectrum, 2017 - Am Soc Microbiol
Plasmids mediate the horizontal transmission of genetic information between bacteria,
facilitating their adaptation to multiple environmental conditions. An especially important …

[HTML][HTML] Interactions between plasmids and other mobile genetic elements affect their transmission and persistence

F Dionisio, R Zilhão, JA Gama - Plasmid, 2019 - Elsevier
Plasmids are genetic elements that play a role in bacterial evolution by providing new genes
that promote adaptation to diverse conditions. Plasmids are also known to reduce bacterial …

Plasmid persistence: costs, benefits, and the plasmid paradox

AC Carroll, A Wong - Canadian journal of microbiology, 2018 - cdnsciencepub.com
Plasmids are extrachromosomal DNA elements that can be found throughout bacteria, as
well as in other domains of life. Nonetheless, the evolutionary processes underlying the …

Plasmid interactions can improve plasmid persistence in bacterial populations

JA Gama, R Zilhão, F Dionisio - Frontiers in Microbiology, 2020 - frontiersin.org
It is difficult to understand plasmid maintenance in the absence of selection and theoretical
models predict the conditions for plasmid persistence to be limited. Plasmid-associated …

[HTML][HTML] An evolutionary perspective on plasmid lifestyle modes

N Hülter, J Ilhan, T Wein, AS Kadibalban… - Current opinion in …, 2017 - Elsevier
Highlights•Plasmid evolution reviewed from the perspective of plasmids.•Mobility, stability,
and indispensability largely determine plasmid lifestyles.•Changes in plasmid traits facilitate …

Beyond horizontal gene transfer: the role of plasmids in bacterial evolution

J Rodríguez-Beltrán, J DelaFuente… - Nature Reviews …, 2021 - nature.com
Plasmids have a key role in bacterial ecology and evolution because they mobilize
accessory genes by horizontal gene transfer. However, recent studies have revealed that …

Natural selection, infectious transfer and the existence conditions for bacterial plasmids

CT Bergstrom, M Lipsitch, BR Levin - Genetics, 2000 - academic.oup.com
Despite the near-ubiquity of plasmids in bacterial populations and the profound contribution
of infectious gene transfer to the adaptation and evolution of bacteria, the mechanisms …

Progress towards understanding the fate of plasmids in bacterial communities

FR Slater, MJ Bailey, AJ Tett… - FEMS microbiology …, 2008 - academic.oup.com
Plasmid-mediated horizontal gene transfer influences bacterial community structure and
evolution. However, an understanding of the forces which dictate the fate of plasmids in …

Antibiotics interfere with the evolution of plasmid stability

T Wein, Y Wang, NF Hülter, K Hammerschmidt… - Current Biology, 2020 - cell.com
Extra-chromosomal genetic elements are important drivers of bacterial evolution, and their
evolutionary success depends on positive selection for the genes they encode. Examples …

Impact of plasmid interactions with the chromosome and other plasmids on the spread of antibiotic resistance

JA Gama, R Zilhão, F Dionisio - Plasmid, 2018 - Elsevier
Naturally occurring plasmids have medical importance given that they frequently code for
virulence or antibiotic resistance. In many cases, plasmids impose a fitness cost to their …