New oral anticoagulants are not superior to warfarin in secondary prevention of stroke or transient ischemic attacks, but lower the risk of intracranial bleeding: insights …

P Sardar, S Chatterjee, WC Wu, E Lichstein, J Ghosh… - PLoS …, 2013 - journals.plos.org
Purpose Patients with Atrial Fibrillation (AF) and prior stroke are classified as high risk in all
risk stratification schemes. A systematic review and meta-analysis was performed to …

Effectiveness and safety of oral anticoagulants among non-valvular atrial fibrillation patients with polypharmacy

GYH Lip, A Keshishian, A Kang… - European Heart …, 2021 - academic.oup.com
Aims Polypharmacy is prevalent among non-valvular atrial fibrillation (NVAF) patients and
presents a potential issue for the effective management of NVAF. This study compared the …

Challenges in comparing the non-vitamin K antagonist oral anticoagulants for atrial fibrillation-related stroke prevention

AJ Camm, KAA Fox, E Peterson - Ep Europace, 2018 - academic.oup.com
The aim of this review is to provide context for meta-analyses interpreting data from phase III
stroke prevention studies of non-vitamin K antagonist oral anticoagulants (NOACs) in …

Major bleeding risk among non‐valvular atrial fibrillation patients initiated on apixaban, dabigatran, rivaroxaban or warfarin: a “real‐world” observational study in the …

GYH Lip, X Pan, S Kamble, H Kawabata… - … journal of clinical …, 2016 - Wiley Online Library
Background Limited data are available about the real‐world safety of non‐vitamin K
antagonist oral anticoagulants (NOAC s). Objectives To compare the major bleeding risk …

Edoxaban in the evolving scenario of non vitamin K antagonist oral anticoagulants imputed placebo analysis and multiple treatment comparisons

P Verdecchia, F Angeli, GYH Lip, G Reboldi - PloS one, 2014 - journals.plos.org
Background Edoxaban recently proved non-inferior to warfarin for prevention of
thromboembolism in patients with non-valvular atrial fibrillation (AF). We conducted an …

Risk of major bleeding in patients with non-valvular atrial fibrillation treated with oral anticoagulants: a systematic review of real-world observational studies

S Deitelzweig, C Farmer, X Luo, L Vo, X Li… - Current Medical …, 2017 - Taylor & Francis
Objective: To conduct a systematic review of real-world (RWD) studies comparing the risk of
major bleeding (MB) among patients with non-valvular atrial fibrillation (NVAF) on direct oral …

[HTML][HTML] Factors associated with non–vitamin K antagonist oral anticoagulants for stroke prevention in patients with new-onset atrial fibrillation: results from the …

BA Steinberg, P Shrader, L Thomas, J Ansell… - American heart …, 2017 - Elsevier
Background Several non–vitamin K antagonist oral anticoagulant (NOAC) alternatives to
warfarin are available for stroke prevention in atrial fibrillation (AF). We aimed to describe …

Efficacy and safety of dabigatran, rivaroxaban, and warfarin for stroke prevention in Chinese patients with atrial fibrillation: the Hong Kong Atrial Fibrillation Project

WH Li, D Huang, CE Chiang, CP Lau, HF Tse… - Clinical …, 2017 - Wiley Online Library
Background Little is known about the comparative effectiveness and safety of non–vitamin K
antagonist oral anticoagulants (NOAC) compared to warfarin in Chinese atrial fibrillation …

Real-world comparative effectiveness, safety, and health care costs of oral anticoagulants in nonvalvular atrial fibrillation patients in the US Department of Defense …

K Gupta, J Trocio, A Keshishian, Q Zhang… - Journal of managed …, 2018 - jmcp.org
BACKGROUND: The ARISTOTLE trial demonstrated that apixaban had significantly lower
rates of stroke/systemic embolism (SE) and major bleeding than warfarin; however, no direct …

Real-world comparisons of direct oral anticoagulants for stroke prevention in Asian patients with non-valvular atrial fibrillation: a systematic review and meta-analysis

YH Chan, HF Lee, TF Chao, CT Wu, SH Chang… - … Drugs and Therapy, 2019 - Springer
Background Whether four direct oral anticoagulants (DOACs) are superior to warfarin
among Asians with non-valvular atrial fibrillation (NVAF) remains unclear in the real-world …