Role of biomarkers for the prevention, assessment, and management of heart failure: a scientific statement from the American Heart Association

SL Chow, AS Maisel, I Anand, B Bozkurt, RA De Boer… - Circulation, 2017 - Am Heart Assoc
Background and Purpose: Natriuretic peptides have led the way as a diagnostic and
prognostic tool for the diagnosis and management of heart failure (HF). More recent …

Biomarker-guided therapy in chronic heart failure: a meta-analysis of randomized controlled trials

GM Felker, V Hasselblad, AF Hernandez… - American heart …, 2009 - Elsevier
BACKGROUND: Measurement of circulating natriuretic peptides has been shown to play an
important role in diagnosis and prognosis in patients with chronic heart failure. Whether …

[HTML][HTML] Biomarkers in routine heart failure clinical care

SK Nadar, MM Shaikh - Cardiac failure review, 2019 - ncbi.nlm.nih.gov
Heart failure is a clinical condition with complex pathophysiology that involves many
different processes. Diagnosis is often difficult in patients presenting for the first time with …

Biomarkers in heart failure: the past, current and future

M Sarhene, Y Wang, J Wei, Y Huang, M Li, L Li… - Heart failure …, 2019 - Springer
Despite the enhanced knowledge of the pathophysiology of heart failure (HF), it still remains
a serious syndrome with substantial morbidity, mortality, and frequent hospitalizations …

Established and emerging roles of biomarkers in heart failure

NE Ibrahim, JL Januzzi Jr - Circulation research, 2018 - Am Heart Assoc
Heart failure (HF) is a complex syndrome with an enormous societal burden in terms of cost,
morbidity, and mortality. Natriuretic peptide testing is now widely used to support diagnosis …

Association of natriuretic peptides with cardiovascular prognosis in heart failure with preserved ejection fraction: secondary analysis of the TOPCAT randomized …

PL Myhre, M Vaduganathan, BL Claggett… - JAMA …, 2018 - jamanetwork.com
Importance Contemporary clinical trials of heart failure with preserved ejection fraction
(HFpEF) apply natriuretic peptide (NP) thresholds to identify patients who are more likely to …

Emerging biomarkers in heart failure

RRJ van Kimmenade, JL Januzzi Jr - Clinical chemistry, 2012 - academic.oup.com
BACKGROUND Until recently, biomarker testing in heart failure (HF) syndromes has been
viewed as an elective supplement to diagnostic evaluation of patients suspected to suffer …

Biomarkers for the diagnosis and management of heart failure

V Castiglione, A Aimo, G Vergaro, L Saccaro… - Heart failure …, 2022 - Springer
Heart failure (HF) is a significant cause of morbidity and mortality worldwide. Circulating
biomarkers reflecting pathophysiological pathways involved in HF development and …

[HTML][HTML] Cardiac biomarkers: new tools for heart failure management

N Iqbal, B Wentworth, R Choudhary… - Cardiovascular …, 2012 - ncbi.nlm.nih.gov
The last decade has seen exciting advances in the field of biomarkers used in managing
patients with heart failure (HF). Biomarker research has broadened our knowledge base …

Strategies for developing biomarkers of heart failure

SA Jortani, SD Prabhu, R Valdes Jr - Clinical chemistry, 2004 - academic.oup.com
Background: Heart failure (HF) is a devastating disease with increasing prevalence in
elderly populations. One-half of all patients die within 5 years of diagnosis. The annual cost …