An imaging-based artificial intelligence model for non-invasive grading of hepatic venous pressure gradient in cirrhotic portal hypertension

Q Yu, Y Huang, X Li, M Pavlides, D Liu, H Luo… - Cell Reports …, 2022 - cell.com
The hepatic venous pressure gradient (HVPG) is the gold standard for cirrhotic portal
hypertension (PHT), but it is invasive and specialized. Alternative non-invasive techniques …

Virtual hepatic venous pressure gradient with CT angiography (CHESS 1601): a prospective multicenter study for the noninvasive diagnosis of portal hypertension

X Qi, W An, F Liu, R Qi, L Wang, Y Liu, C Liu, Y Xiang… - Radiology, 2019 - pubs.rsna.org
Purpose To develop and validate a computational model for estimating hepatic venous
pressure gradient (HVPG) based on CT angiographic images, termed virtual HVPG, to …

Diagnosis of clinically significant portal hypertension using CT-and MRI-based vascular model

C Wang, Y Huang, C Liu, F Liu, X Hu, X Kuang, W An… - Radiology, 2023 - pubs.rsna.org
Background Currently, the hepatic venous pressure gradient (HVPG) remains the reference
standard for diagnosis of clinically significant portal hypertension (CSPH) but is limited by its …

Management of portal hypertension

AV Kulkarni, A Rabiee, A Mohanty - Journal of clinical and experimental …, 2022 - Elsevier
Portal hypertension is the cause of the clinical complications associated with cirrhosis. The
primary complications of portal hypertension are ascites, acute variceal bleed, and hepatic …

Global sensitivity analysis of hepatic venous pressure gradient (HVPG) measurement with a stochastic computational model of the hepatic circulation

T Wang, F Liang, Z Zhou, X Qi - Computers in Biology and Medicine, 2018 - Elsevier
Hepatic venous pressure gradient (HVPG) is a widely employed surrogate of portal pressure
gradient (PPG) in the diagnosis of portal hypertension (PHT). However, little is known about …

Deep convolutional neural network-aided detection of portal hypertension in patients with cirrhosis

Y Liu, Z Ning, N Örmeci, W An, Q Yu, K Han… - Clinical …, 2020 - Elsevier
Background & Aims Noninvasive and accurate methods are needed to identify patients with
clinically significant portal hypertension (CSPH). We investigated the ability of deep …

Development and validation of a radiomics signature for clinically significant portal hypertension in cirrhosis (CHESS1701): a prospective multicenter study

F Liu, Z Ning, Y Liu, D Liu, J Tian, H Luo, W An… - …, 2018 - thelancet.com
Clinically significant portal hypertension (CSPH) is associated with an incremental risk of
esophageal varices and overt clinical decompensations. However, hepatic venous pressure …

Liver imaging in precision medicine

J Dong, X Qi - EBioMedicine, 2018 - thelancet.com
In late 1895, Wilhelm Roentgen ignited a disease diagnostics revolution with the discovery
of x-rays, which opened a new era for medical imaging. Imaging is swiftly evolving from …

Noninvasive imaging assessment of portal hypertension: where are we now and where does the future lie?

S Wan, X Liu, H Jiang, Z Teng… - Expert Review of Molecular …, 2021 - Taylor & Francis
The comprehensive management of chronic liver disease and subsequent portal
hypertension (PH) remains a challenge in clinical treatment. The consequences of PH are …

Network meta-analysis: noninvasive imaging modalities for identifying clinically significant portal hypertension

Y Hai, W Chong, JR Eisenbrey, F Forsberg - Digestive diseases and …, 2022 - Springer
Background Although measurement of the hepatic venous pressure gradient (HVPG) is the
current reference standard for obtaining portal venous pressures, several noninvasive …