Synaptic plasticity in the form of long-term potentiation (LTP) plays a critical role in the
formation of a Pavlovian fear association. However, the role that synaptic plasticity plays in …

Retrieval of a memory appears to render it unstable until the memory is once again re-
stabilized or reconsolidated. Although the occurrence and consequences of reconsolidation …

Understanding the neurophysiology of fear extinction has important implications for the
treatment of post-traumatic stress disorders. Here we report that fear conditioning resulted in …

Much of the research on long-term potentiation (LTP) is motivated by the question of whether
changes in synaptic strength similar to LTP underlie learning and memory. Here we discuss …

Abstract Although glutamate receptor 1 (GluR1)‐containing α‐amino‐3‐hydroxyl‐5‐methyl‐
4‐isoxazole‐propionate receptors (GluR1‐AMPARs) are implicated in synaptic plasticity, it …

There is compelling evidence that L-alpha-amino-3-hydroxy-5-methylisoxazole-4-
propionate (AMPA) glutamate receptors containing the GluR1 subunit contribute to the …

Rats treated with the AMPA receptor-facilitating drug 1-(quinoxolin-6-ylcarbonyl) piperidine
(BDP-12) during training acquired fear conditioning to a tone faster than vehicle-treated …

Long-term potentiation (LTP) at sensory input synapses to the lateral amygdala (LA) is a
candidate mechanism for memory storage during fear conditioning. We evaluated the effect …

Extinction of conditioned fear is an active learning process requiring N-methyl-D-aspartate
receptors (NMDARs), but the timing, location, and neural mechanisms of NMDAR-mediated …

Pavlovian fear conditioning, a simple form of associative learning, is thought to involve the
induction of associative, NMDA receptor–dependent long-term potentiation (LTP) in the …