Rapid neurotransmission is mediated through a superfamily of Cys-loop receptors that
includes the nicotinic acetylcholine (nAChR), γ-aminobutyric acid (GABAA), serotonin (5 …

Despite extensive studies on nicotinic acetylcholine receptors (nAChRs) and homologues,
details of acetylcholine binding are not completely resolved. Here, we report the crystal …

Acetylcholine‐binding protein (AChBP) is a novel protein with high similarity to the
extracellular domain of the nicotinic acetylcholine receptor. AChBP lacks the …

Acetylcholine-binding protein (AChBP) is a water-soluble protein released from molluscan
glial cells and modulates ACh-mediated synaptic transmission. Acetylcholine-binding …

The crystal structure of acetylcholine-binding protein (AChBP) from the mollusk Lymnaea
stagnalis is the established model for the ligand binding domains of the ligand-gated ion …

The recent characterization of an acetylcholine binding protein (AChBP) from the fresh water
snail, Lymnaea stagnalis, shows it to be a structural homolog of the extracellular domain of …

Upon ligand binding at the subunit interfaces, the extracellular domain of the nicotinic
acetylcholine receptor undergoes conformational changes, and agonist binding …

Nicotinic acetylcholine receptors (nAChRs) are in the superfamily of cys‐loop receptors, and
are widely expressed in the nervous system where they participate in a variety of …

The atomic determination of the acetylcholine binding protein (AChBP), a molluscan
cholinergic protein, homologous to the amino-terminal extracellular domain of nicotinic …

Nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated ion channels that
belong to the Cys-loop receptor superfamily. These receptors are allosteric proteins that …