The structure and integrity of the ageing brain is interchangeably linked to physical health,
and cardiometabolic risk factors (CMRs) are associated with dementia and other brain …

Brain structure in later life reflects both influences of intrinsic aging and those of lifestyle,
environment and disease. We developed a deep neural network model trained on brain MRI …

Brain age is becoming a widely applied imaging-based biomarker of neural aging and
potential proxy for brain integrity and health. We estimated multimodal and modality-specific …

The deviation between chronological age and age predicted using brain MRI is a putative
marker of overall brain health. Age prediction based on structural MRI data shows high …

Brain development and aging are dynamic processes that unfold over years on multiple
levels in both healthy and disordered individuals. Recent studies have revealed a disparity …

The brain-age paradigm is proving increasingly useful for exploring aging-related disease
and can predict important future health outcomes. Most brain-age research uses structural …

Aging alters brain structure and function. Personal health markers and modifiable lifestyle
factors are related to individual brain aging as well as to the risk of developing Alzheimer's …

Normal aging is associated with both structural changes in many brain regions and
functional declines in several cognitive domains with advancing age. Advanced …

The adult human brain shrinks slowly with age, but the regional specificity and tissue class
specificity of this loss is unclear. Subjects (n= 122) were healthy aged participants in a …

Abstracts Metabolic syndrome (MetS) is characterized by a constellation of metabolic risk
factors, including obesity, hypertriglyceridemia, low high-density lipoprotein (HDL) levels …