Background Accumulating evidence supports that tumor growth and cancer relapse are
driven by cancer stem cells. Our previous work has demonstrated the existence of CD90+ …

Intratumor molecular heterogeneity of hepatocellular carcinoma is partly attributed to the
presence of hepatic cancer stem cells (CSCs). Different CSC populations defined by various …

Hepatocellular carcinoma (HCC) is one of the world's most aggressive diseases and carries
a poor prognosis for patients. Recent evidence suggests that HCC is organized by cancer …

Solid tumors are thought to contain cancer stem cells (CSCs) as a distinct population
responsible for tumor relapse and metastasis due to their abilities to self-renew, differentiate …

There has been considerable interest in cancer stem cells (CSCs) among cancer biologists
and clinicians, most likely because of their role in the heterogeneity of cancer and their …

Recent evidence suggests that a subset of hepatocellular carcinomas (HCCs) are derived
from liver cancer stem cells (LCSCs). In order to isolate and characterize LCSCs, reliable …

Cancer stem cells (CSCs) are a small subpopulation in cancer, have been proposed to be
cancer-initiating cells, and have been shown to be responsible for chemotherapy resistance …

Hepatocellular carcinoma (HCC) is an aggressive disease with a poor clinical outcome. The
cancer stem cell (CSC) model states that tumour growth is powered by a subset of tumour …

Background Hepatocellular carcinoma is one of the most common cancers and the second
leading cause of cancer-related deaths worldwide. Only a small proportion of patients …

Background & Aims: Recent efforts in stem cell biology suggest that tumors are organized in
a hierarchy of heterogeneous cell populations and that the capability to maintain tumor …