COVID-19: consider cytokine storm syndromes and immunosuppression

P Mehta, DF McAuley, M Brown, E Sanchez… - The lancet, 2020 - thelancet.com
As of March 12, 2020, coronavirus disease 2019 (COVID-19) has been con firmed in 125
048 people worldwide, carrying a mortality of approximately 3· 7%, 1 compared with a …

Coronavirus disease-2019: A review on the disease exacerbation via cytokine storm and concurrent management

H Sunkara, SMR Dewan - International immunopharmacology, 2021 - Elsevier
Abstract Setting up treatment strategies is the highest concern today to reduce the fatality of
COVID-19. Due to a very new kind of virus attack, no specific treatment has been discovered …

Dynamic changes in lymphocyte subsets and parallel cytokine levels in patients with severe and critical COVID-19

Y Liu, W Tan, H Chen, Y Zhu, L Wan, K Jiang… - BMC infectious …, 2021 - Springer
Background The lack of knowledge regarding the pathogenesis and host immune response
during SARS-CoV-2 infection has limited the development of effective treatments. Thus, we …

Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine …

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …

Comparing the cytokine storms of COVID-19 and pandemic influenza

LM Pacheco-Hernández… - Journal of interferon & …, 2022 - liebertpub.com
Emerging respiratory viruses are major health threats due to their potential to cause massive
outbreaks. Over the past 2 years, the coronavirus disease 2019 (COVID-19) pandemic has …

COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has posed a significant threat to global health. This …

Advances in the research of cytokine storm mechanism induced by Corona Virus Disease 2019 and the corresponding immunotherapies

C Chen, X ZHANG, Z JU, W HE - Chinese journal of burns, 2020 - pesquisa.bvsalud.org
ABSTRACT Corona Virus Disease 2019 (COVID-19) has seriously affected the treatment of
patients and social stability. In the later stage of disease, some COVID-19 patients may …

Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recently
emerged in Wuhan, Hubei-China, as responsible for the coronavirus disease 2019 (COVID …

COVID 19: in the eye of the cytokine storm

G Liuzzo, C Patrono - 2021 - academic.oup.com
System in New York between 21 March and 28 April 2020. Serum levels of four inflammatory
cytokines were analysed upon admission with a rapid multiplex test: interleukin (IL)-6, IL-8 …

Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
caused the greatest pandemic of our century. Many of the deaths related to it are due to a …