Cystic fibrosis (CF) is an autosomal recessive disease that was previously a fatal pediatric
disease with no treatment; however, due to scientific advancements, the median age of …

After 25 years of intensive search, there is not yet a cure for cystic fibrosis (CF). However, the
quest has led to major breakthroughs in understanding the basic disease defect and …

Objectives Study of currently approved drugs and exploration of future clinical development
pipeline therapeutics for cystic fibrosis, and possible limitations in their use. Methods …

Advances in cystic fibrosis therapies : Current Opinion in Pediatrics Advances in cystic fibrosis
therapies : Current Opinion in Pediatrics Log in or Register Subscribe to journalSubscribe Get …

INTRODUCTION Cystic fibrosis (CF) is a genetic disorder that leads to chronic multisystem
disease consisting of chronic sinopulmonary infections, malabsorption, and nutritional …

As the field continues to change rapidly and new therapies are being identified, CF has
become a paradigm for the application of concepts such as translational medicine, genomic …

The rate of progress in the field continues to accelerate with new knowledge informing the
development of innovative therapies. This has already led to tangible substantial and …

Cystic fibrosis is one of the most widespread fatal genetic diseases in the United States. A
specific flawed gene triggers this scourge of infancy and childhood and causes a cascade of …

Since the first description of Cystic fibrosis (CF) more than 75 y ago, significant advances
have been made in understanding its pathogenesis and in developing specific therapies …

Cystic fibrosis (CF) is the most common genetic disorder in Caucasian individuals, with an
incidence of 1/2,500–3,500 live births. When CF was first described in 1938, most children …