Identification of potential complementary serum biomarkers to differentiate prostate cancer from benign prostatic hyperplasia using gel‐and lectin‐based proteomics …

JJ Jayapalan, KL Ng, AHA Razack… - Electrophoresis, 2012 - Wiley Online Library
Diagnosis of prostate cancer (PC a) is currently much reliant on the invasive and time‐
consuming transrectal ultrasound‐guided biopsy of the prostate gland, particularly in light of …

Inflammation: an important parameter in the search of prostate cancer biomarkers

S Bergamini, E Bellei, L Reggiani Bonetti, E Monari… - Proteome science, 2014 - Springer
Background A more specific and early diagnostics for prostate cancer (PCa) is highly
desirable. In this study, being inflammation the focus of our effort, serum protein profiles …

Discovery of serum protein biomarkers for prostate cancer progression by proteomic analysis

JA Al-Ruwaili, SET Larkin, BA Zeidan… - Cancer genomics & …, 2010 - cgp.iiarjournals.org
Background: The incidence of prostate cancer (PCa) has increased in recent years due to
the aging of the population and increased testing; however, mortality rates have remained …

[HTML][HTML] Potential urinary protein biomarker candidates for the accurate detection of prostate cancer among benign prostatic hyperplasia patients

TA Haj-Ahmad, MAK Abdalla, Y Haj-Ahmad - Journal of Cancer, 2014 - ncbi.nlm.nih.gov
Abstract Globally, Prostate cancer (PCa) is the most frequently occurring non-cutaneous
cancer, and is the second highest cause of cancer mortality in men. Serum prostate specific …

Identification of plasma protein profiles associated with risk groups of prostate cancer patients

M Nordström, C Wingren, C Rose… - PROTEOMICS …, 2014 - Wiley Online Library
Purpose Early detection of prostate cancer (PC) using prostate‐specific antigen (PSA) in
blood reduces PC‐death among unscreened men. However, due to modest specificity of …

[HTML][HTML] Combined serum and EPS-urine proteomic analysis using iTRAQ technology for discovery of potential prostate cancer biomarkers

M Zhang, L Chen, Z Yuan, Z Yang, Y Li… - Discovery …, 2016 - discoverymedicine.com
Prostate cancer (PCa) is one of the most common malignant tumors and a major cause of
cancer-related death for men worldwide. The aim of our study was to identify potential non …

The role of proteomics in prostate cancer research: biomarker discovery and validation

E Pin, C Fredolini, EF Petricoin III - Clinical biochemistry, 2013 - Elsevier
PURPOSE: Prostate Cancer (PCa) represents the second most frequent type of tumor in
men worldwide. Incidence increases with patient age and represents the most important risk …

Putative protein markers in the sera of men with prostatic neoplasms

S Lehrer, J Roboz, H Ding, S Zhao… - BJU …, 2003 - Wiley Online Library
OBJECTIVE To describe the preliminary identification of serum proteins that may be
diagnostic markers in prostate cancer. PATIENTS AND METHODS The study included 11 …

[HTML][HTML] Profiling the proteoforms of urinary prostate-specific antigen by capillary electrophoresis–mass spectrometry

AB Moran, E Domínguez-Vega, J Nouta, T Pongracz… - Journal of …, 2021 - Elsevier
Early detection of prostate cancer may lead to the overdiagnosis and overtreatment of
patients as well as missing significant cancers. The current diagnostic approach uses …

The role of proteomics in biomarker development for improved patient diagnosis and clinical decision making in prostate cancer

CL Tonry, E Leacy, C Raso, SP Finn, J Armstrong… - Diagnostics, 2016 - mdpi.com
Prostate Cancer (PCa) is the second most commonly diagnosed cancer in men worldwide.
Although increased expression of prostate-specific antigen (PSA) is an effective indicator for …