Y Cao, J Wang, F Jian, T Xiao, W Song, A Yisimayi… - BioRxiv, 2021 - biorxiv.org
Abstract The SARS-CoV-2 B. 1.1. 529 variant (Omicron) contains 15 mutations on the receptor-binding domain (RBD). How Omicron would evade RBD neutralizing antibodies …
E Cameroni, JE Bowen, LE Rosen, C Saliba… - Nature, 2022 - nature.com
The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …
SARS-CoV-2 is a newly emerged coronavirus responsible for the current COVID-19 pandemic that has resulted in more than one million infections and 73,000 deaths,. Vaccine …
D Planas, N Saunders, P Maes, F Guivel-Benhassine… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant was first identified in November 2021 in Botswana and South Africa,–. It has since spread to many countries and is expected to …
Abstract The coronavirus disease 2019 (COVID-19) pandemic presents an urgent health crisis. Human neutralizing antibodies that target the host ACE2 receptor-binding domain …
M Li, F Lou, H Fan - Signal Transduction and Targeted Therapy, 2022 - nature.com
On December 23, 2021, five groups published their research results of clinical-approved monoclonal antibodies, convalescent serum, and vaccine serum against B. 1.1. 529 …
T Zhou, L Wang, J Misasi, A Pegu, Y Zhang, DR Harris… - Science, 2022 - science.org
The rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B. 1.1. 529 (Omicron) variant and its resistance to neutralization by vaccinee and convalescent …
Neutralizing antibodies (nAbs) to SARS-CoV-2 hold powerful potentials for clinical interventions against COVID-19 disease. However, their common genetic and biologic …
The highly mutated SARS-CoV-2 Omicron (B. 1.1. 529) variant has been shown to evade a substantial fraction of neutralizing antibody responses elicited by current vaccines that …