A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection

H Liu, M Yuan, D Huang, S Bangaru, F Zhao… - Cell host & …, 2021 - cell.com
Coronaviruses have caused several human epidemics and pandemics including the
ongoing coronavirus disease 2019 (COVID-19). Prophylactic vaccines and therapeutic …

[HTML][HTML] Antibody evasion properties of SARS-CoV-2 Omicron sublineages

S Iketani, L Liu, Y Guo, L Liu, JFW Chan, Y Huang… - Nature, 2022 - nature.com
The identification of the Omicron (B. 1.1. 529.1 or BA. 1) variant of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) in Botswana in November 2021 1 immediately …

Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers

K Vanshylla, C Fan, M Wunsch, N Poopalasingam… - Cell host & …, 2022 - cell.com
A fraction of COVID-19 convalescent individuals mount a potent antibody response to SARS-
CoV-2 with cross-reactivity to SARS-CoV-1. To uncover their humoral response in detail, we …

Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study

KM Hastie, H Li, D Bedinger, SL Schendel… - Science, 2021 - science.org
Antibody-based therapeutics and vaccines are essential to combat COVID-19 morbidity and
mortality after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

Isolation of a panel of ultra-potent human antibodies neutralizing SARS-CoV-2 and viral variants of concern

AA Gorchakov, SV Kulemzin, SV Guselnikov… - Cell Discovery, 2021 - nature.com
In the absence of virus-targeting small-molecule drugs approved for the treatment and
prevention of COVID-19, broadening the repertoire of potent SARS-CoV-2-neutralizing …

Neutralizing antibodies against the SARS-CoV-2 Omicron variant BA. 1 following homologous and heterologous CoronaVac or BNT162b2 vaccination

SMS Cheng, CKP Mok, YWY Leung, SS Ng… - Nature medicine, 2022 - nature.com
The Omicron variant is rapidly becoming the dominant SARS-CoV-2 virus circulating
globally. It is important to define reductions in virus neutralizing activity in the serum of …

Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants

S Moriyama, Y Anraku, S Taminishi, Y Adachi… - Nature …, 2023 - nature.com
SARS-CoV-2 Omicron subvariants have evolved to evade receptor-binding site (RBS)
antibodies that exist in diverse individuals as public antibody clones. We rationally selected …

The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA. 1 evolution

A Moulana, T Dupic, AM Phillips, J Chang, AA Roffler… - Elife, 2023 - elifesciences.org
The Omicron BA. 1 variant of SARS-CoV-2 escapes convalescent sera and monoclonal
antibodies that are effective against earlier strains of the virus. This immune evasion is …

[HTML][HTML] Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition

AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein… - Cell host & …, 2021 - cell.com
Antibodies targeting the SARS-CoV-2 spike receptor-binding domain (RBD) are being
developed as therapeutics and are a major contributor to neutralizing antibody responses …

Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron

H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin… - Nature, 2022 - nature.com
Abstract The Omicron (B. 1.1. 529) variant of SARS-CoV-2 emerged in November 2021 and
is rapidly spreading among the human population. Although recent reports reveal that the …