In the context of bone development and regeneration, the intimate association of the
vascular endothelium with osteogenic cells suggests that endothelial cells (ECs) may …

It is well accepted, that there is communication between osteoblasts and endothelial cells.
However, the influence of endothelial cells on the differentiation of bone precursors into …

Background Improved understanding of the interactions between bone cells and endothelial
cells involved in osteogenesis should aid the development of new strategies for bone tissue …

Angiogenesis is a tightly regulated process involved in growth, repair, and bone remodeling.
Several studies have shown that there is a reciprocal regulation and functional relationship …

Bone regeneration is a complex, well-orchestrated process based on the interactions
between osteogenesis and angiogenesis, observed in both physiological and pathological …

Angiogenesis is a fundamental process in bone formation, remodeling, and regeneration.
Moreover, for the regeneration of bone in tissue engineering applications, it is essential to …

Bone development and remodeling depend on complex interactions between bone-forming
osteoblasts and other cells present within the bone microenvironment, particularly …

Early vascularization of a composite in a critical bone defect is a prerequisite for ingrowth of
osteogenic reparative cells to regenerate bone, since lack of vessels does not ensure a …

Background and Aims Bone is a highly vascularized tissue reliant on the close spatial and
temporal connection between blood vessels and bone cells to maintain skeletal integrity …

Aim: The size of a bone defect limits the ingrowth of bone-forming cells. Endothelial cell–like
differentiated precursor cells (endothelial progenitor cells, EPC) enhance the …