Abstract The Wellcome Trust Case Control Consortium (WTCCC) primary genome-wide
association (GWA) scan on seven diseases, including the multifactorial autoimmune disease …

Aims/hypothesis Given the potential shared aetiology between type 1 and type 2 diabetes,
we aimed to identify any genetic regions associated with both diseases. For associations …

Meta-analyses of genome-wide association studies (GWAS) have improved our
understanding of the genetic foundations of a number of diseases, including diabetes …

Genome-wide association studies (GWAS) have facilitated a substantial and rapid rise in the
number of confirmed genetic susceptibility variants for type 2 diabetes (T2D). Approximately …

Type 2 diabetes refers to a group of disparate metabolic diseases, which are typically
characterized by insulin resistance in peripheral tissues, together with impaired insulin …

We are all witnesses to a period of astonishing progress in our understanding of the genetic
basis of diabetes, and the advances of recent months are arguably the most important made …

Over the past 3 years, there has been a dramatic increase in the number of confirmed type 2
diabetes (T2D) susceptibility loci, most arising through the implementation of genome-wide …

Aims/hypothesis We conducted genome-wide association studies (GWASs) and expression
quantitative trait loci (eQTL) analyses to identify and characterise risk loci for type 2 diabetes …

Over the past 8 years, the genetics of complex traits have benefited from an unprecedented
advancement in the identification of common variant loci for diseases such as type 2 …

With the exception of rare mono-genic disorders, most type 2 diabetes results from the
interaction of genetic variation at multiple different chromosomal sites with environmental …