Stem-cell-based strategies for the treatment of Parkinson's disease

CL Parish, E Arenas - Neurodegenerative Diseases, 2007 - karger.com
Background: Cell transplantation to replace lost neurons in neurodegenerative diseases
such as Parkinson's disease (PD) offers a hopeful prospect for many patients. Previously …

Cell-based therapeutic approaches for Parkinson's disease: progress and perspectives

SV Anisimov - Reviews in the Neurosciences, 2009 - degruyter.com
Motor djsfunctions in Parkinson's disease a· e believed to be primarily due to the
degeneration of dopamincrgic neurons located in the substantia nigra pars compacta …

Stem cell-based therapies for Parkinson disease

Z Liu, HH Cheung - International journal of molecular sciences, 2020 - mdpi.com
Parkinson disease (PD) is a neurological movement disorder resulting primarily from
damage to and degeneration of the nigrostriatal dopaminergic pathway. The pathway …

An update on human stem cell-based therapy in Parkinson's disease

C González, S Bonilla, A Isabel Flores… - Current stem cell …, 2016 - ingentaconnect.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease and it is characterized by the progressive loss of dopaminergic neurons …

Current state of stem cell research for the treatment of Parkinson's disease

M Gerlach, H Braak, A Hartmann, WH Jost, P Odin… - Journal of …, 2002 - Springer
Current findings suggest that multipotent stem cells may be suitable for cell replacement
therapies in the treatment of neurodegenerative disorders. Embryonic stem (ES) cells are …

[HTML][HTML] Stem cell treatments for Parkinson's disease

TB Stoker - 2019 - europepmc.org
Parkinson's disease (PD) manifests with a typical movement disorder, due to the loss of
dopaminergic neurons of the substantia nigra. There are no disease-modifying treatments …

From bench to bed: the potential of stem cells for the treatment of Parkinson's disease

A Morizane, JY Li, P Brundin - Cell and tissue research, 2008 - Springer
Parkinson's disease (PD) is the most common movement disorder. The neuropathology is
characterized by the loss of dopamine neurons in the substantia nigra pars compacta …

Stem cell-based therapies in Parkinson's disease: future hope or current treatment option?

K Loewenbrück, A Storch - Journal of neurology, 2011 - Springer
Parkinson's disease (PD) is one of the most frequent neurodegenerative diseases and
represents a major therapeutic challenge because of the so far missing therapeutic means …

Stem Cell-Based Approaches in Parkinson's Disease Research

MS Kim, S Yoon, J Choi, YJ Kim, G Lee - International Journal of …, 2024 - ijstemcell.com
Parkinson's disease (PD) is a neurodegenerative condition characterized by the loss of
midbrain dopaminergic neurons, leading to motor symptoms. While current treatments …

Repairing the brain: cell replacement using stem cell-based technologies

C Henchcliffe, M Parmar - Journal of Parkinson's Disease, 2018 - content.iospress.com
Current approaches to cell replacement therapy in Parkinson's disease are strongly focused
on the dopamine system, with the view that restoring dopaminergic inputs in a localized and …