Maternal immune activation, central nervous system development and behavioral phenotypes

E Minakova, BB Warner - Birth defects research, 2018 - Wiley Online Library
Maternal immune activation (MIA) refers to a maternal immune system triggered by
infectious or infectious‐like stimuli. A cascade of cytokines and immunologic alterations are …

[HTML][HTML] Translational opportunities in the prenatal immune environment: Promises and limitations of the maternal immune activation model

MD Bauman, J Van de Water - Neurobiology of disease, 2020 - Elsevier
The prenatal environment, and in particular, the maternal-fetal immune environment, has
emerged as a targeted area of research for central nervous system (CNS) diseases with …

Maternal inflammation and its ramifications on fetal neurodevelopment

HK Kwon, GB Choi, JR Huh - Trends in immunology, 2022 - cell.com
Exposure to heightened inflammation in pregnancy caused by infections or other
inflammatory insults has been associated with the onset of neurodevelopmental and …

Maternal immune activation and related factors in the risk of offspring psychiatric disorders

F Conway, AS Brown - Frontiers in psychiatry, 2019 - frontiersin.org
Maternal immune activation (MIA) at the time of gestation has been linked to increased risk
of neurodevelopmental psychiatric disorders. Animal and human models have been used to …

Maternal immune activation as an epidemiological risk factor for neurodevelopmental disorders: Considerations of timing, severity, individual differences, and sex in …

MB Hall, DE Willis, EL Rodriguez… - Frontiers in …, 2023 - frontiersin.org
Epidemiological evidence suggests that one's risk of being diagnosed with a
neurodevelopmental disorder (NDD)—such as autism, ADHD, or schizophrenia—increases …

Virus-induced maternal immune activation as an environmental factor in the etiology of autism and schizophrenia

A Massrali, D Adhya, DP Srivastava… - Frontiers in …, 2022 - frontiersin.org
Maternal immune activation (MIA) is mediated by activation of inflammatory pathways
resulting in increased levels of cytokines and chemokines that cross the placental and blood …

Prenatal maternal immune activation and brain development with relevance to psychiatric disorders

G Scola, A Duong - Neuroscience, 2017 - Elsevier
Growing evidence from epidemiological studies strongly suggests maternal infection as a
risk factor for psychiatric disorders including bipolar disorder, schizophrenia, and autism …

[HTML][HTML] Brain changes in a maternal immune activation model of neurodevelopmental brain disorders

L Bergdolt, A Dunaevsky - Progress in neurobiology, 2019 - Elsevier
The developing brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …

Maternal immune activation: Implications for neuropsychiatric disorders

ML Estes, AK McAllister - Science, 2016 - science.org
Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum
disorder and schizophrenia. Animal models corroborate this link and demonstrate that …

Maternal immune activation and neuropsychiatric illness: a translational research perspective

AS Brown, U Meyer - American Journal of Psychiatry, 2018 - Am Psychiatric Assoc
Epidemiologic studies, including prospective birth cohort investigations, have implicated
maternal immune activation in the etiology of neuropsychiatric disorders. Maternal infectious …