Editing nature: Reconceptualizing biotechnology governance

JJ Monast - BCL Rev., 2018 - HeinOnline
CRISPR-Cas9 (CRISPR) and other advances in gene editing techniques are fostering a
rapid evolution within the field of biotechnology. Scientists can now modify the DNA of living …

CRISPR regulation

M Darnovsky, N Comfort, FS Alkuraya… - Issues in Science and …, 2019 - JSTOR
As the debate about heritable genome editing unfolds, divergent perspectives are coming
more clearly into view. Those who see it as offering little or no benefit while posing …

“Editing”: A productive metaphor for regulating CRISPR

B Merriman - The American Journal of Bioethics, 2015 - Taylor & Francis
O'Keefe and colleagues'(2015) study of popular media identifies two predominant
metaphors in descriptions of CRISPR-based genetic technologies: editing and targeting. 1 …

Regulatory Silos: Assessing the United States' Regulation of Biotechnology in the Age of Gene Drives

C Dooley - Geo. Envtl. L. Rev., 2017 - HeinOnline
The advent of CRISPR gene editing technology has moved the use of gene drives,
genetically engineering an organism to push a preferred gene through a target population …

[PDF][PDF] CRISPR democracy: Gene editing and the need for inclusive deliberation

S Jasanoff, JB Hurlbut, K Saha - Issues in Science and Technology, 2015 - ask-force.org
Not since the early, heady days of recombinant DNA (rDNA) has a technique of molecular
biology so gripped the scientific imagination as the CRISPR-Cas9 method of gene editing …

Making space for CRISPR: scientists' translation work to make gene editing a legitimate technology

M Svingen, L Jahren - Science and Public Policy, 2024 - academic.oup.com
This paper focuses on scientists working with CRISPR in Norway, where genetic
modification is thought to be a particularly stigmatized technology with strict regulation and a …

Rules for sculpting ecosystems: Gene drives and responsive science

KM Esvelt - Gene editing, law, and the environment, 2017 - taylorfrancis.com
As a technology capable of altering wild populations and associated ecosystems, CRISPR-
based gene drive challenges existing law and scientific tradition. While most technologies …

Afterword: Governing Gene Editing: A Constitutional Conversation

S Hilgartner - Gene Editing, Law, and the Environment, 2017 - taylorfrancis.com
The rise of gene editing technologies such as CRISPR and gene drives has significantly
increased the ability of humans to edit genomes, making it much easier to alter the human …

CRISPR ethics: moral considerations for applications of a powerful tool

C Brokowski, M Adli - Journal of molecular biology, 2019 - Elsevier
With the emergence of CRISPR technology, targeted editing of a wide variety of genomes is
no longer an abstract hypothetical, but occurs regularly. As application areas of CRISPR are …

Anticipating emerging biotechnology threats: A case study of CRISPR

KM Vogel, SB Ouagrham-Gormley - Politics and the Life Sciences, 2018 - cambridge.org
This article discusses the contingencies and complexities of CRISPR. It outlines key
problems regarding off-target effects and replication of experimental work that are important …