Background We previously described mutation rates of BRAF V600E, RAS, RET-PTC and
PAX8-PPARγ in pediatric subjects with well-differentiated thyroid cancer (WDTC). We …

Background: Well-differentiated thyroid cancer (WDTC) incidence in pediatrics is rising, most
being papillary thyroid carcinoma (PTC). The objective of the study was to assess the …

Background: Molecular testing (MT) enhances the diagnostic accuracy of thyroid fine-needle
aspiration biopsy, reducing the need for diagnostic lobectomy in adult patients with …

Purpose: Differentiated thyroid cancer (DTC) is rare in children. Previous studies have
suggested that it has different clinicopathologic features and mutation profiles compared …

Background: Pediatric papillary thyroid carcinoma (PTC) is a rare malignancy, but with
increasing incidence. Pediatric PTCs have distinct clinical and pathological features and …

Background Pediatric papillary thyroid carcinoma (PTC) is clinically and biologically distinct
from adult PTC. We sequenced a cohort of clinically annotated pediatric PTC cases enriched …

PURPOSE In 2014, data from a comprehensive multiplatform analysis of 496 adult papillary
thyroid cancer samples reported by The Cancer Genome Atlas project suggested that …

Context Pediatric differentiated thyroid cancer (DTC) differs from adult DTC in its underlying
genetics and clinicopathological features. In this report, we studied these aspects in 48 …

Objectives The primary objective of this study was to determine the prevalence of BRAF
V600E and TERT promoter mutations in paediatric and young adult patients with papillary …

Simple Summary Papillary thyroid carcinoma (PTC) in pediatric patients shows different
characteristics compared with PTC in adults. In this large mono-institutional cohort of …