The functional roles of lipid rafts in T cell activation, immune diseases and HIV infection and prevention

C Luo, K Wang, D Liu, Y Li, Q Zhao - Cellular & molecular immunology, 2008 - nature.com
The first appearance of lipid rafts, or lipid rafts-like structure, was occasionally observed by
cryo-electronic microscopy in 1980s as cavity, such as caveolae. However, the fully …

[HTML][HTML] Lipid rafts and their roles in T-cell activation

V Hořejší - Microbes and infection, 2005 - Elsevier
Lipid rafts are defined as detergent-resistant membrane microdomains of specific lipid and
protein composition. They are involved in many aspects of cell biology, including T-cell …

[HTML][HTML] Lipid rafts in T cell signalling and disease

EC Jury, F Flores-Borja, PS Kabouridis - Seminars in cell & developmental …, 2007 - Elsevier
Lipid rafts is a blanket term used to describe distinct areas in the plasma membrane rich in
certain lipids and proteins and which are thought to perform diverse functions. A large …

Lipid rafts in immune signalling: current progress and future perspective

P Varshney, V Yadav, N Saini - Immunology, 2016 - Wiley Online Library
Lipid rafts are dynamic assemblies of proteins and lipids that harbour many receptors and
regulatory molecules and so act as a platform for signal transduction. They float freely within …

Viruses, lipid rafts and signal transduction

S Rauch, OT Fackler - Signal Transduction, 2007 - Wiley Online Library
Lipid rafts are defined as highly dynamic microdomains in cellular membranes that are
enriched in sphingolipids, cholesterol and raft‐targeted proteins. This particular lipid and …

Raft membrane domains: from a liquid-ordered membrane phase to a site of pathogen attack

FG van der Goot, T Harder - Seminars in immunology, 2001 - Elsevier
While the existence of cholesterol/sphingolipid (raft) membrane domains in the plasma
membrane is now supported by strong experimental evidence, the structure of these …

[PDF][PDF] Float on: lipid rafts in the lifecycle of HIV

D Wilflingseder, H Stoiber - Front Biosci, 2007 - article.imrpress.com
[Frontiers in Bioscience 12, 2124-2135, January 1, 2007] 2124 Float on: lipid rafts in the
lifecycle of HIV Doris Wilflingseder Page 1 [Frontiers in Bioscience 12, 2124-2135, January 1 …

Lipid rafts: structure, function and role in HIV, Alzheimer's and prion diseases

J Fantini, N Garmy, R Mahfoud, N Yahi - Expert reviews in molecular …, 2002 - cambridge.org
The fluid mosaic model of the plasma membrane has evolved considerably since its original
formulation 30 years ago. Membrane lipids do not form a homogeneous phase consisting of …

Lipid raft-based membrane order is important for antigen-specific clonal expansion of CD4+ T lymphocytes

D Schieffer, S Naware, W Bakun, AK Bamezai - BMC immunology, 2014 - Springer
Background Lipid rafts are cholesterol and saturated lipid-rich, nanometer sized membrane
domains that are hypothesized to play an important role in compartmentalization and …

Lipid rafts in cytokine signaling

R Rao, B Logan, K Forrest, TL Roszman… - Cytokine & growth factor …, 2004 - Elsevier
Lipid rafts are established as critical structures for a variety of cellular processes, including
immune cell activation. Beyond their importance for initial immune cell activation at the …