Photoredox Radical Cascade Cyclization of 2‐Alkynylarylnitriles in Visible Light: Direct Access to 3‐Amino‐1‐indenones

S Rajput, D Garg, N Jain - Advanced Synthesis & Catalysis, 2024 - Wiley Online Library
A photoinduced direct synthesis of 3‐amino‐1‐indenones via radical cascade cyclization
strategy is demonstrated. The methodology involves a domino reaction between 2 …

Photoinduced cyclization of aryl ynones with 4-alkyl-DHPs for the divergent synthesis of indenones, thioflavones and spiro [5.5] trienones

WC Yang, Y Sun, LY Shen, X Xie, B Yu - Molecular Catalysis, 2023 - Elsevier
A direct and efficient visible-light-induced cascade cyclization reaction of aryl ynones with 4-
alkyl-DHPs for the divergent synthesis of indenones, thioflavones and spiro [5.5] trienones …

Visible light-induced N-radical 5-exo/6-endo cyclization of alkenyl amides: facile access to isoindolinones/isoquinolinones

ZY Lei, K Hu, YX He, S Geng, LN Chen… - Organic & …, 2022 - pubs.rsc.org
An efficient N-centered radical intramolecular cyclization reaction of alkenyl amides induced
by visible light was described. In this process, an alkenyl amide underwent 5-exo/6-endo …

Controllable Synthesis of Cyclopenta[b]indolines via Photocatalytic Fluoroalkylative Radical Cyclization Cascade of Ynamides

J Li, Y Zhou, J Luo, H Chen, H Qi, H Zheng… - Organic Letters, 2024 - ACS Publications
A de novo method for direct construction of cyclopenta [b] indolines via a photocatalytic
fluoroalkylative radical cyclization cascade of ynamides has been established, which …

Photoredox-mediated N-centered radical addition/semipinacol rearrangement for the convenient synthesis of β-amino (spiro) cyclic ketones

TC Ma, S Yao, MM Qiao, F Yuan, DQ Shi… - Organic Chemistry …, 2021 - pubs.rsc.org
A visible light photoredox-catalyzed N-centered radical addition/semipinacol rearrangement
cascade of cycloalkanol-substituted 1H-indenes or styrenes with N-arylsulfonyl protected 1 …

Recent applications of radical cascade reaction in the synthesis of functionalized 1-indenones

Y Zhang, K Sun, Q Lv, X Chen, L Qu, B Yu - Chinese Chemical Letters, 2019 - Elsevier
Indenones are important scaffolds in natural products, biologically active molecules as well
as functional materials. Recently, radical cascade cyclization has emerged as an efficient …

A Visible‐Light‐Mediated Oxidative CN Bond Formation/Aromatization Cascade: Photocatalytic Preparation of N‐Arylindoles

S Maity, N Zheng - Angewandte Chemie International Edition, 2012 - Wiley Online Library
Indoles are heterocyclic motifs that are embedded in a large number of bioactive natural
products and pharmaceuticals.[1] As such, the search for sustainable and more efficient …

Controlled Photochemical Synthesis of Substituted Isoquinoline-1,3,4(2H)-triones, 3-Hydroxyisoindolin-1-ones, and Phthalimides via Amidyl Radical Cyclization …

MB Reddy, K Prasanth, R Anandhan - Organic Letters, 2022 - ACS Publications
We report a controlled radical cyclization cascade of isoquinoline-1, 3, 4 (2 H)-triones, 3-
hydroxyisoindolin-1-ones, and phthalimides from o-alkynylated benzamides by metal-free …

Green Light Triggered Radical Annulation for the Synthesis of Indenone by Metal‐Free Photocatalysis

X He, JQ Ji, MY Zhao, CH Ma, DD Zhang… - European Journal of …, 2024 - Wiley Online Library
Low‐energy light, endowing with excellent characteristics of lower energy, fewer side
reactions, more abundance in solar light. The scenario has been developed for the …

Trifluoromethyl radical triggered radical cyclization of N-benzoyl ynamides leading to isoindolinones

M Cassé, C Nisole, H Dossmann, Y Gimbert… - Science China …, 2019 - Springer
Under photocatalytic reductive conditions, trifluoromethyl radical addition onto an ynamide
followed by cyclization on a benzoyl moiety produces diverse isoindolinone platforms with …