Early or late gestational exposure to maternal immune activation alters neurodevelopmental trajectories in mice: an integrated neuroimaging, behavioral, and …

E Guma, P do Couto Bordignon, GA Devenyi… - Biological …, 2021 - Elsevier
Background Exposure to maternal immune activation (MIA) in utero is a risk factor for
neurodevelopmental disorders later in life. The impact of the gestational timing of MIA …

Differential effects of early or late exposure to prenatal maternal immune activation on mouse embryonic neurodevelopment

E Guma, M Bordeleau… - Proceedings of the …, 2022 - National Acad Sciences
Exposure to maternal immune activation (MIA) in utero is a risk factor for
neurodevelopmental and psychiatric disorders. MIA-induced deficits in adolescent and adult …

Maternal immune activation alters fetal brain development and enhances proliferation of neural precursor cells in rats

KJ Baines, DM Hillier, FL Haddad… - Frontiers in …, 2020 - frontiersin.org
Maternal immune activation (MIA) caused by exposure to pathogens or inflammation during
critical periods of neurodevelopment is a major risk factor for behavioral deficits and …

Maternal immune activation during pregnancy alters postnatal brain growth and cognitive development in nonhuman primate offspring

RM Vlasova, AM Iosif, AM Ryan, LH Funk… - Journal of …, 2021 - Soc Neuroscience
Human epidemiological studies implicate exposure to infection during gestation in the
etiology of neurodevelopmental disorders. Animal models of maternal immune activation …

Sequential perturbations to mouse corticogenesis following in utero maternal immune activation

CP Canales, ML Estes, K Cichewicz, K Angara… - Elife, 2021 - elifesciences.org
In utero exposure to maternal immune activation (MIA) is an environmental risk factor for
neurodevelopmental and neuropsychiatric disorders. Animal models provide an opportunity …

Behavioral, neuroanatomical, and molecular correlates of resilience and susceptibility to maternal immune activation

FS Mueller, J Scarborough, SM Schalbetter… - Molecular …, 2021 - nature.com
Infectious or noninfectious maternal immune activation (MIA) is an environmental risk factor
for psychiatric and neurological disorders with neurodevelopmental etiologies. Whilst there …

Preliminary evidence of neuropathology in nonhuman primates prenatally exposed to maternal immune activation

RK Weir, R Forghany, SEP Smith, PH Patterson… - Brain, behavior, and …, 2015 - Elsevier
Maternal infection during pregnancy increases the risk for neurodevelopmental disorders in
offspring. Rodent models have played a critical role in establishing maternal immune …

The impact of maternal immune activation on embryonic brain development

F McEwan, JD Glazier, R Hager - Frontiers in Neuroscience, 2023 - frontiersin.org
The adult brain is a complex structure with distinct functional sub-regions, which are
generated from an initial pool of neural epithelial cells within the embryo. This transition …

[HTML][HTML] Maternal immune activation in rodent models: A systematic review of neurodevelopmental changes in gene expression and epigenetic modulation in the …

RM Woods, JM Lorusso, HG Potter, JC Neill… - Neuroscience & …, 2021 - Elsevier
Maternal immune activation (mIA) during pregnancy is hypothesised to disrupt offspring
neurodevelopment and predispose offspring to neurodevelopmental disorders such as …

[HTML][HTML] Maternal immune activation during pregnancy impacts on brain structure and function in the adult offspring

S Kreitz, A Zambon, M Ronovsky, L Budinsky… - Brain, Behavior, and …, 2020 - Elsevier
Gestational infection constitutes a risk factor for the occurrence of psychiatric disorders in the
offspring. Activation of the maternal immune system (MIA) with subsequent impact on the …