Systematic review: efficacy and safety of switching patients between reference and biosimilar infliximab

BG Feagan, G Lam, C Ma… - Alimentary …, 2019 - Wiley Online Library
Background Biosimilar versions of widely prescribed drugs, including the tumour‐necrosis
factor antagonist infliximab, are becoming increasingly available. As biosimilars are not …

Long‐term efficacy and safety of biosimilar infliximab (CT‐P13) after switching from originator infliximab: open‐label extension of the NOR‐SWITCH trial

GL Goll, KK Jørgensen, J Sexton… - Journal of internal …, 2019 - Wiley Online Library
Background and objectives The 52‐week, randomized, double‐blind, noninferiority,
government‐funded NOR‐SWITCH trial demonstrated that switching from infliximab …

Switching from infliximab to biosimilar in inflammatory bowel disease: overview of the literature and perspective

Á Milassin, A Fábián, T Molnár - Therapeutic advances in …, 2019 - journals.sagepub.com
Background: Biological therapy has revolutionized the treatment of inflammatory bowel
disease (IBD). After the expiration of patents for biological innovator products, development …

Switching between reference biologics and biosimilars for the treatment of rheumatology, gastroenterology, and dermatology inflammatory conditions: considerations …

R Moots, V Azevedo, JL Coindreau, T Dörner… - Current rheumatology …, 2017 - Springer
Abstract Purpose of Review Biosimilars of the reference biologic therapeutics infliximab,
etanercept, adalimumab, and rituximab are entering the market. Clinical and real-world data …

Systematic review: non-medical switching of infliximab to CT-P13 in inflammatory bowel disease

EJ Bernard, RN Fedorak, V Jairath - Digestive Diseases and Sciences, 2020 - Springer
Abstract Background and Aims Biosimilar approval, such as Inflectra™(CT-P13) for treating
ulcerative colitis (UC) and Crohn's disease (CD), has reduced direct drug costs. Though …

Multiple switches from the originator infliximab to biosimilars is effective and safe in inflammatory bowel disease: a prospective multicenter cohort study

J Hanzel, JM Jansen, RWF Ter Steege… - Inflammatory bowel …, 2022 - academic.oup.com
Background Though a single nonmedical switch from the originator infliximab (IFX) to a
biosimilar is considered effective and safe for most patients with inflammatory bowel disease …

[HTML][HTML] Switching from an originator anti-TNF to a biosimilar in patients with inflammatory bowel disease: can it be recommended? A systematic review

JP Gisbert, M Chaparro - Gastroenterologia y Hepatologia, 2018 - Elsevier
Aim To review the effectiveness and safety of switching from an originator anti-TNF
(Remicade®) to a biosimilar (CT-P13) in patients with inflammatory bowel disease (IBD) …

Switching from infliximab innovator to biosimilar in patients with inflammatory bowel disease: a 12‐month multicentre observational prospective cohort study

EMH Schmitz, PJ Boekema… - Alimentary …, 2018 - Wiley Online Library
Background Infliximab biosimilars have become available for treatment of inflammatory
bowel disease (IBD). However, data showing long‐term safety and effectiveness of …

Outcomes after double switching from originator Infliximab to biosimilar CT‐P13 and biosimilar SB2 in patients with inflammatory bowel disease: a 12‐month …

N Trystram, V Abitbol, J Tannoury… - Alimentary …, 2021 - Wiley Online Library
Background There are few data regarding multiple switching from the originator Infliximab to
its biosimilars. Aim To assess outcomes and patient perspectives in a prospective manner …

Systematic switch from innovator infliximab to biosimilar infliximab in inflammatory chronic diseases in daily clinical practice: the experience of Cochin University …

J Avouac, A Moltó, V Abitbol, A Etcheto… - Seminars in Arthritis and …, 2018 - Elsevier
Objective To investigate effectiveness of systematic switching treatment from innovator
infliximab to biosimilar infliximab, and its associated factors. Methods In this prospective …