Severe influenza remains unusual in its virulence for humans. Complications or ultimately
death arising from these infections are often associated with hyperinduction of …

Influenza A virus is a significant cause of morbidity and mortality worldwide. Severe
influenza is recognized as a clinical syndrome, characterized by hyperinduction of …

Influenza virus is a significant pathogen in humans and animals with the ability to cause
extensive morbidity and mortality. Exuberant immune responses induced following infection …

A severe inflammatory immune response with hypercytokinemia occurs in patients
hospitalized with severe influenza, such as avian influenza A (H5N1), A (H7N9), and …

Aberrant pulmonary immune responses are linked to the pathogenesis of multiple human
respiratory viral infections. Elevated cytokine and chemokine production “cytokine storm” …

Influenza A virus is one of the major human pathogens. The influenza infection can pass out
without any subclinical symptoms or infestation can appear in upper respiratory tract as well …

Cytokine storm defines a dysregulation of and an excessively exaggerated immune
response most often accompanying selected viral infections and several autoimmune …

Influenza viruses are still a serious threat to human health. Cytokines are essential for cell-to-
cell communication and viral clearance in the immune system, but excessive cytokines can …

Influenza epidemics and pandemics cause significant morbidity and mortality worldwide
associated with severe immunopathology in the lung, and the mechanisms of such …

The cytokine storm has captured the attention of the public and the scientific community
alike, and while the general notion of an excessive or uncontrolled release of …