Several chronic bioassays have been conducted in multiple strains of mice in which various
concentrations of arsenate or arsenite were administered in the drinking water without a …

A remarkable feature of the carcinogenicity of inorganic arsenic is that while human
exposures to high concentrations of inorganic arsenic in drinking water are associated with …

The relationship of exposure and tissue concentration of parent chemical and metabolites
over prolonged exposure is a critical issue for chronic toxicities mediated by metabolite (s) …

Recent studies have suggested that polymorphisms in the methylation of inorganic arsenic
(iAs) exist in animals and humans. Methylation of iAs is an important step in the elimination …

Exposure to the drinking water contaminant arsenate is a daily occurrence and there are
concerns that this exposure may lead to cancer. Although the acute dispositional effects of …

Accurate assessment of adverse health effects attributable to ingestion of inorganic arsenic
(As) present in contaminated soils requires determination of the internal dose of metal …

Arsenic (As) is ubiquitous in the earth's crust, with typical dietary intake in developed
countries< 1 μg/kg bw/d, and atypical groundwater exposures in developing countries …

A physiologically based pharmacokinetic model for exposure to inorganic arsenic in
hamsters and rabbits has been developed. The model in its present state simulates three …

Arsenic is a ubiquitous contaminant, with typical dietary intake below 1 μg/kg bw/d and
drinking water exposures up to 50 μg/kg bw/d. Arsenic exposures are associated with …

Inorganic arsenic in drinking water is associated with increased cancers of the skin, liver,
urinary bladder, and kidneys. An uncertainty in estimating the risk from inorganic arsenic is …