Prognostic value of a modified‑immune scoring system in patients with pathological T4 colorectal cancer

G Dorjkhorloo, B Erkhem-Ochir… - Oncology …, 2024 - spandidos-publications.com
Tumor-infiltrating immune cells, such as lymphocytes and macrophages, have been
associated with tumor aggressiveness, prognosis and treatment response in colorectal …

Validation of the prognostic value of CD3 and CD8 cell densities analogous to the Immunoscore® by stage and location of colorectal cancer: an independent patient …

E Alwers, JN Kather, M Kloor, A Brobeil… - The Journal of …, 2023 - Wiley Online Library
In addition to the traditional staging system in colorectal cancer (CRC), the Immunoscore®
has been proposed to characterize the level of immune infiltration in tumor tissue and as a …

Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction

B Mlecnik, M Tosolini, A Kirilovsky, A Berger… - Journal of clinical …, 2011 - ascopubs.org
Purpose The prognosis of patients with colorectal cancer has sometimes proved uncertain;
thus, the prognostic significance of immune criteria was compared with that of the tumor …

Simplified and optimized immune score for colorectal cancer microenvironment

H Nakane, T Sudo, A Kawahara, T Yomoda… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: Immunoscore (IS) is an important evaluation method for the tumor immune
microenvironment (TIME); however, formal IS analysis requires designated reagents and a …

A nomogram‑based immunoprofile predicts clinical outcomes for stage II and III human colorectal cancer

L Wang, N Chang, L Wu, J Li… - Molecular and …, 2021 - spandidos-publications.com
An immunoscore for colorectal cancer (CRC) has higher prognostic significance than the
TNM staging system. However, the tumor immune microenvironment contains various …

Immune scores in colorectal cancer: Where are we?

D Malka, A Lièvre, T André, J Taïeb, M Ducreux… - European Journal of …, 2020 - Elsevier
There is growing evidence that the immune system may prevent the occurrence, growth and
metastatic diffusion of colorectal cancer (CRC). The role played by the adaptive immune …

Validation of the Immunoscore (IM) as a prognostic marker in stage I/II/III colon cancer: Results of a worldwide consortium-based analysis of 1,336 patients.

J Galon, B Mlecnik, F Marliot, FS Ou, CB Bifulco… - 2016 - ascopubs.org
3500 Background: Mounting evidence indicates an enhanced lymphocytic reaction as an
informative prognostic indicator in colon cancer (CC). The IM methodology has been defined …

Clinical performance of the consensus immunoscore in colon cancer in the Asian population from the multicenter international SITC study

B Mlecnik, T Torigoe, G Bindea, B Popivanova, M Xu… - Cancers, 2022 - mdpi.com
Simple Summary Research interest in Immuno-oncology and the role of the adaptative
immune system in the progression and prognosis of colon cancer (CC) is growing. In this …

Rational bases for the use of the Immunoscore in routine clinical settings as a prognostic and predictive biomarker in cancer patients

A Kirilovsky, F Marliot, C El Sissy… - International …, 2016 - academic.oup.com
Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) tumor, nodes, metastasis (TNM) classification system based on tumor features …

Multicenter international study of the consensus immunoscore for the prediction of relapse and survival in early-stage colon cancer

B Mlecnik, A Lugli, G Bindea, F Marliot, C Bifulco… - Cancers, 2023 - mdpi.com
Simple Summary This work determines the predictive value of the consensus Immunoscore
in 1885 patients with AJCC/UICC-TNM stage I-II Colon Cancer (CC) from North American …