Gene expression patterns of dengue virus-infected children from nicaragua reveal a distinct signature of increased metabolism
P Loke, SN Hammond, JM Leung, CC Kim… - PLoS neglected …, 2010 - journals.plos.org
Background Infection with dengue viruses (DENV) leads to a spectrum of disease outcomes.
The pathophysiology of severe versus non-severe manifestations of DENV infection may be …
The pathophysiology of severe versus non-severe manifestations of DENV infection may be …
Differential gene expression changes in children with severe dengue virus infections
MD de Kruif, TE Setiati, ATA Mairuhu… - PLoS neglected …, 2008 - journals.plos.org
Background The host response to dengue virus infection is characterized by the production
of numerous cytokines, but the overall picture appears to be complex. It has been suggested …
of numerous cytokines, but the overall picture appears to be complex. It has been suggested …
Temporal dynamics of the transcriptional response to dengue virus infection in Nicaraguan children
Dengue is the most prevalent mosquito-borne human illness worldwide. The ability to
predict disease severity during the earliest days of the illness is a long-sought, but …
predict disease severity during the earliest days of the illness is a long-sought, but …
Differences in global gene expression in peripheral blood mononuclear cells indicate a significant role of the innate responses in progression of dengue fever but not …
S Ubol, P Masrinoul, J Chaijaruwanich… - The Journal of …, 2008 - academic.oup.com
Background. Dengue virus infection causes an array of symptoms ranging from dengue
fever (DF) to dengue hemorrhagic fever (DHF). The pathophysiological processes behind …
fever (DF) to dengue hemorrhagic fever (DHF). The pathophysiological processes behind …
Sequential waves of gene expression in patients with clinically defined dengue illnesses reveal subtle disease phases and predict disease severity
P Sun, J García, G Comach, MT Vahey… - PLoS neglected …, 2013 - journals.plos.org
Background Dengue virus (DENV) infection can range in severity from mild dengue fever
(DF) to severe dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS) …
(DF) to severe dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS) …
Time since onset of disease and individual clinical markers associate with transcriptional changes in uncomplicated dengue
CAM van de Weg, HJ van den Ham… - PLoS Neglected …, 2015 - journals.plos.org
Background Dengue virus (DENV) infection causes viral haemorrhagic fever that is
characterized by extensive activation of the immune system. The aim of this study is to …
characterized by extensive activation of the immune system. The aim of this study is to …
Host gene expression profiling of dengue virus infection in cell lines and patients
J Fink, F Gu, L Ling, T Tolfvenstam, F Olfat… - PLoS neglected …, 2007 - journals.plos.org
Background Despite the seriousness of dengue-related disease, with an estimated 50–100
million cases of dengue fever and 250,000–500,000 cases of dengue hemorrhagic …
million cases of dengue fever and 250,000–500,000 cases of dengue hemorrhagic …
Patterns of gene transcript abundance in the blood of children with severe or uncomplicated dengue highlight differences in disease evolution and host response to …
DNA microarrays and specific reverse-transcription polymerase chain reaction assays were
used to reveal transcriptional patterns in the blood of children presenting with dengue shock …
used to reveal transcriptional patterns in the blood of children presenting with dengue shock …
Gene expression profiling during early acute febrile stage of dengue infection can predict the disease outcome
Background We report the detailed development of biomarkers to predict the clinical
outcome under dengue infection. Transcriptional signatures from purified peripheral blood …
outcome under dengue infection. Transcriptional signatures from purified peripheral blood …
RNA-Seq analysis of peripheral blood mononuclear cells reveals unique transcriptional signatures associated with disease progression in dengue patients
A Banerjee, S Shukla, AD Pandey, S Goswami… - Translational …, 2017 - Elsevier
Patients infected with Dengue virus usually present a mild, self-limiting febrile dengue
infection (DI) that occasionally leads to a potentially lethal complication, called the severe …
infection (DI) that occasionally leads to a potentially lethal complication, called the severe …
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