A Major Diplotaxis harra-Derived Bioflavonoid Glycoside as a Protective Agent against Chemically Induced Neurotoxicity and Parkinson's Models; In Silico Target …

AF Ahmed, ZH Wen, AH Bakheit, OA Basudan… - Plants, 2022 - mdpi.com
Oxidative stress and chronic inflammation have a role in developing neurodegenerative
diseases such as Parkinson's disease (PD) and inflammatory movement disorders such as …

[HTML][HTML] A comprehensive assessment of phytochemicals from Phyla nodiflora (L.) Greene as a potential enzyme inhibitor, and their biological potential: An in-silico, in …

A Alafnan, MF Nadeem, SF Ahmad, M Sarfraz… - Arabian Journal of …, 2023 - Elsevier
This work explored Phyla nodiflora (L.) Greene as a potential source of the bioactive
medicinal agent. In this aspect, methanol (PN-M) and dichloromethane (PN-D) extracts were …

Study on the therapeutic material basis and effect of Acanthopanax senticosus (Rupr. et Maxim.) Harms leaves in the treatment of ischemic stroke by PK-PD analysis …

Y Wang, S Liu, R Wang, L Shi, Z Liu, Z Liu - Food & function, 2020 - pubs.rsc.org
Leaves of Acanthopanax senticosus (Rupr. et Maxim.) Harms (ASL) have revealed
significant biological activity in the treatment of ischemic stroke diseases. However, there …

Nootropic and anti-Alzheimer's actions of medicinal plants: molecular insight into therapeutic potential to alleviate Alzheimer's neuropathology

MS Uddin, A Al Mamun, MT Kabir, M Jakaria… - Molecular …, 2019 - Springer
Medicinal plants are the backbone of modern medicine. In recent times, there is a great urge
to discover nootropic medicinal plants to reverse cognitive dysfunction owing to their less …

Molecular docking and molecular dynamics approach to identify potential compounds in Huperzia squarrosa for treating Alzheimer's disease

BT Tung, TTT Hang, NB Kim, NH Nhung… - … of Complementary and …, 2022 - degruyter.com
Objectives Alzheimer's disease (AD) is a lingering progressive neurodegenerative disorder
that causes patients to lose cognitive function. The enzyme Acetylcholinesterase (AChE) …

Flavonoid derivatives as potential cholinesterase inhibitors in Scopolamine-induced amnesic mice: an in vitro, in vivo and integrated computational approach

FA Al-Joufi, SWA Shah, M Shoaib, M Ghias, Shafiullah… - Brain Sciences, 2022 - mdpi.com
Flavonoids are one of the most exciting types of phenolic compounds with a wide range of
bioactive benefits. A series of flavone derivatives (F1–F5) were previously synthesized from …

Experimental evidence and mechanism of action of some popular neuro-nutraceutical herbs

A Kumar, A Konar, S Garg, SC Kaul… - Neurochemistry …, 2021 - Elsevier
Brain and neuronal circuits constitute the most complex organ networks in human body.
They not only control and coordinate functions of all other organs, but also represent one of …

Comparative analysis of stilbene and benzofuran neolignan derivatives as acetylcholinesterase inhibitors with neuroprotective and anti-inflammatory activities

M Nagumo, M Ninomiya, N Oshima, T Itoh… - Bioorganic & Medicinal …, 2019 - Elsevier
Stilbenes and benzofuran neolignans are important groups of plant phenolics therefore they
play a significant role in plants and human health. The objective of this study was to …

The promising guide to LC–MS analysis and cholinesterase activity of Luffa cylindrica (L.) fruit using in vitro and in-silico analyses

SA Singh, C Vellapandian - Future Journal of Pharmaceutical Sciences, 2023 - Springer
Background Luffa cylindrica (L.) is an annual climbing plant that produces fibrous fruit and
can also be used as a vegetable in northern parts of India. Various studies have been …

In vitro and in silico approaches to appraise Polygonum maritimum L. as a source of innovative products with anti-ageing potential

MJ Rodrigues, S Slusarczyk, Ł Pecio… - Industrial Crops and …, 2018 - Elsevier
Different Polygonum species have in vitro neuroprotective properties and are traditionally
used for their anti-ageing benefits. In this context this work explored for the first time P …