Papillomaviruses in anogenital cancer as a model to understand the role of viruses in human cancers

H zur Hausen - Cancer Research, 1989 - AACR
Infections with specific types of human papillomaviruses (HPV) have emerged as necessary
but not sufficient factors for the development, at least, of the majority of cervical, vulvar …

Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis

H Hausen - Journal of the National Cancer Institute, 2000 - academic.oup.com
During the past 20 years, several types of human papillomaviruses (HPVs) have been
identified that cause specific types of cancers. The etiology of cancer of the cervix has been …

Human papillomaviruses in the pathogenesis of anogenital cancer

H zur Hausen - Virology, 1991 - Elsevier
Substantial experimental evidence accumulated over the past 8 years has indicated an
etiological role for specific human papillomavirus (HPV) types in anogenital cancer and its …

Human papillomaviruses and genital cancer

H Pfister - Advances in Cancer Research, 1987 - Elsevier
Publisher Summary Papillomaviruses are clearly proven to be the etiologic agents of
anogenital lesions, with the potential to progress to squamous cell carcinomas. Viral …

Oncogenic activities of human papillomaviruses

ME McLaughlin-Drubin, K Münger - Virus research, 2009 - Elsevier
Infectious etiologies for certain human cancers have long been suggested by
epidemiological studies and studies with experimental animals. Important support for this …

Papillomavirus infections—a major cause of human cancers

H Zur Hausen - Biochimica et biophysica acta (BBA)-reviews on cancer, 1996 - Elsevier
The papillomavirus family represents a remarkably heterogeneous group of viruses. At
present, 77 distinct genotypes have been identified in humans and partial sequences have …

Human papillomaviruses and associated malignancies.

RM Alani, K Münger - Journal of clinical oncology, 1998 - ascopubs.org
The human papillomaviruses (HPVS) are small DNA tumor viruses that infect epithelial cells
and induce proliferative lesions. Substantial epidemiologic data along with in vitro and in …

Role of human papillomavirus in the pathogenesis of genital tract warts and cancer

TC Wright, RM Richart - Gynecologic oncology, 1990 - Elsevier
During the last decade a large number of clinical, epidemiological, and experimental studies
have elucidated the role of HPV in the pathogenesis of anogenital cancer. Although the …

Human papillomavirus and cervical carcinogenesis

MA Stanley - Best Practice & Research Clinical Obstetrics & …, 2001 - Elsevier
Epidemiological studies show that infection with a subset of genital human papillomavirus
(HPV) infections is the major risk factor for the subsequent development of cervical cancer …

Functions of human papillomavirus proteins

M Scheffner, H Romanczuk, K Münger… - Human pathogenic …, 1994 - Springer
Cervical cancer is the second leading cause of deaths from cancer among women
worldwide with approximately 500 000 deaths annually. Epidemiologic studies have …