The frequency and description of side effects secondaiy to the subcutaneous application of
SPf66 malaria vaccine and placebo are reported for each dose of application in the …

This paper reports the efficacy results of the randomized, placebo-controlled, field trial of
SPf66 malaria vaccine in Costa Marques, Rondonia, Brazil. This region is characterized by …

In the first field trial with synthetic malaria vaccine SPf66 in a large population naturally
exposed to malaria, 9957 persons> 1 year old and residing on the Colombian Pacific coast …

In preparation for an efficacy trial of malaria vaccine SPf66 in Thailand, a series of
overlapping Phase I trials were conducted of US-manufactured SPf66. Here, two clinical lots …

In preparation for a recently reported, independent field trial of SPf66 malaria vaccine
efficacy in Thailand, we first established the safety and immunogenicity of two clinical lots of …

A total of 537 subjects were randomized to receive either SPf66 malaria vaccine against
Plasmodium falciparum or placebo in three doses (days 0, 30 and 180). Subjects completing …

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Preclinical and clinical studies have established the safety and immunogenicity of the
chemically synthesised SPf66 malaria vaccine. The present study is a phase III randomised …

A crucial step has been made in the development of malaria vaccines. The first trial of SPf66
in Africa and the first outside Latin America has been completed in an area of very intense …

As part of the first trial of the SPf66 malaria vaccine in Africa, three randomized double-blind
placebo-controlled studies of SPf66 have been conducted in a highly endemic area of …