Clinical application of antibody immunity against SARS-CoV-2: Comprehensive review on immunoassay and immunotherapy

ZJ Cheng, B Li, Z Zhan, Z Zhao, M Xue, P Zheng… - Clinical Reviews in …, 2022 - Springer
The current COVID-19 global pandemic poses immense challenges to global health, largely
due to the difficulty to detect infection in the early stages of the disease, as well as the …

Evaluation of SARS-CoV-2 neutralization assays for antibody monitoring in natural infection and vaccine trials

AM Sholukh, A Fiore-Gartland, ES Ford, YJ Hou, V Tse… - medRxiv, 2020 - medrxiv.org
Determinants of protective immunity against SARS-CoV-2 infection require the development
of well-standardized, reproducible antibody assays to be utilized in concert with clinical trials …

Severe acute respiratory syndrome coronavirus 2 neutralizing antibody titers in convalescent plasma and recipients in New Mexico: an open treatment study in …

SB Bradfute, I Hurwitz, AV Yingling, C Ye… - The Journal of …, 2020 - academic.oup.com
Background Convalescent plasma (CP) is a potentially important therapy for coronavirus
disease 2019 (COVID-19). However, knowledge regarding neutralizing antibody (NAb) titers …

Naturally acquired SARS-CoV-2 immunity persists for up to 11 months following infection

V De Giorgi, KA West, AN Henning… - The Journal of …, 2021 - academic.oup.com
Background Characterizing the kinetics of the antibody response to severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) is of critical importance to developing strategies …

Convalescent plasma therapy for the treatment of patients with COVID‐19: assessment of methods available for antibody detection and their correlation with …

H Harvala, ML Robb, N Watkins, S Ijaz… - Transfusion …, 2021 - Wiley Online Library
Introduction The lack of approved specific therapeutic agents to treat coronavirus disease
(COVID‐19) associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV …

COVID-19 convalescent plasma is more than neutralizing antibodies: a narrative review of potential beneficial and detrimental co-factors

D Focosi, M Franchini, L Pirofski, T Burnouf… - Viruses, 2021 - mdpi.com
COVID-19 convalescent plasma (CCP) is currently under investigation for both treatment
and post-exposure prophylaxis. The active component of CCP mediating improved outcome …

Neutralizing antibodies responses to SARS-CoV-2 in COVID-19 inpatients and convalescent patients

X Wang, X Guo, Q Xin, Y Pan, J Li, Y Chu, Y Feng… - MedRxiv, 2020 - medrxiv.org
Background COVID-19 is a pandemic with no specific antiviral treatments or vaccines. The
urgent needs for exploring the neutralizing antibodies from patients with different clinical …

[HTML][HTML] Quantification of SARS-CoV-2 antibodies with eight commercially available immunoassays

L Weidner, S Gänsdorfer, S Unterweger… - Journal of Clinical …, 2020 - Elsevier
Since the emergence of SARS-CoV-2 numerous antibody assays have become available,
demonstrating different performance characteristics. This study focused on a quantitative …

Rapidly increasing SARS-CoV-2 neutralization by intravenous immunoglobulins produced from plasma collected during the 2020 pandemic

MR Farcet, M Karbiener, J Schwaiger, R Ilk, TR Kreil - bioRxiv, 2021 - biorxiv.org
Abstract Immunoglobulin (IG) lots (N= 176) released since March 2020 were tested for
SARS-CoV-2 neutralizing antibodies, with first positive results for September 2020 lots …

[HTML][HTML] Donors for SARS-CoV-2 convalescent plasma for a controlled clinical trial: donor characteristics, content and time course of SARS-CoV-2 neutralizing …

S Körper, B Jahrsdörfer, VM Corman, J Pilch… - Transfusion Medicine …, 2021 - karger.com
Background: Convalescent plasma is one of the treatment options for COVID-19 which is
currently being investigated in many clinical trials. Understanding of donor and product …