The aim of this study was to design and develop a new pH-responsive nano-platform for
controlled and targeted delivery of anticancer drugs. Engineering of pH-responsive …

In this work, gold embedded chitosan nanoparticles (Au@ CS NPs) were fabricated by a one-
pot method. The benzaldehyde-terminated poly [(2-methacryloyloxy) ethyl …

Cancer is considered to be one of the leading causes of morbidity and mortality worldwide
and nanotechnology was shown to have a unique potential to enhance the therapeutic …

Abstract Methoxy-poly (ethylene glycol)(mPEG)-Asp-Cys was synthesized by ring opening
polymerization, and its characterization by 1H nuclear magnetic resonance (NMR) showed …

Encapsulation of therapeutic molecules into nanocarrier is an extensively explored strategy
to treat cancer more effectively. In this study, pH-responsive targeting dual-agent delivery …

In this study, gold nanoparticles (AuNPs) were modified with a negatively charged peptide,
Fmoc-GCE, for use as nanocarriers of a positively charged anti-tumor drug, doxorubicin …

Abstract pH-sensitive smart polymeric nanocarriers have been under development in the
field of biomedicine due to permeabilization the physiological barriers readily to address the …

Methotrexate (MTX) has poor water solubility and low bioavailability, and cancer cells can
become resistant to it, which limits its safe delivery to tumor sites and reduces its clinical …

Due to its inherent membrane structure, a nanostructure enveloped by an active cell
membrane possesses distinctive characteristics such as prolonged presence in the …

Tumor-responsive nanocarriers are highly valuable and demanded for smart anticancer
drug delivery, where a quick release of chemotherapeutic drugs in tumors is preferred …