Background Epilepsy is one of the most common brain disorder and, despite the possible
use of several therapeutic options, many patients continue to have seizures for their entire …

Microglia, the dynamic innate immune cells of the central nervous system, become activated
in epilepsy. The process of microglial activation in epilepsy results in the creation of an …

Abstract The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB/Akt)/mechanistic
target of rapamycin (mTOR) signaling pathway has been associated with several …

The present study reports the behavioral, electrophysiological, and neuropathological
effects of cannabidiol (CBD), a major non-psychotropic constituent of Cannabis sativa, in the …

Background and Purpose A non‐psychoactive phytocannabinoid, cannabidiol (CBD), shows
promising results as an effective potential antiepileptic drug in some forms of refractory …

Epilepsy is a neurological disorder characterized by the presence of seizures and
neuropsychiatric comorbidities. Despite the number of antiepileptic drugs, one-third of …

Anticonvulsant effects of cannabidiol (CBD), a nonpsychoactive cannabinoid, have not been
investigated in the juvenile brain. We hypothesized that CBD would attenuate epileptiform …

Cannabis sativa has been associated with contradictory effects upon seizure states despite
its medicinal use by numerous people with epilepsy. We have recently shown that the …

Studies have demonstrated the neuroprotective effect of cannabidiol (CBD) and other
Cannabis sativa L. derivatives on diseases of the central nervous system caused by their …

Cannabidiol (CBD) has gained attention as a therapeutic agent and is purported to have
immunomodulatory, neuroprotective, and anti-seizure effects. Here, we determined the …