There is a need for new biomarkers of atherosclerotic cardiovascular disease (ACVD), the
main cause of death globally. Ceramides, a class of potent bioactive lipid mediators, have …

Ceramides are bioactive lipids that act as secondary messengers for both intra-and inter-
cellular signaling. Elevated plasma concentrations of ceramides are associated with multiple …

Ceramide is a core molecule of sphingolipid metabolism that causes selective insulin
resistance and dyslipidemia. Research on its involvement in cardiovascular diseases has …

Background and aims The relationship between ceramides and the risk of mortality among
patients with coronary artery disease (CAD) is currently relatively sparse. This prospective …

Growing evidence suggests that ceramides play an important role in the development of
atherosclerotic and valvular heart disease. Ceramides are biologically active sphingolipids …

Objective—Ceramides are sphingolipids involved with cellular signaling. Synthesis of
ceramides occurs in all tissues. Ceramides accumulate within tissues and the blood plasma …

Background Elevated plasma ceramides are independent predictors of cardiovascular
disease and mortality in patients with advanced epicardial coronary artery disease. Our …

Ceramides are bioactive lipids that have an important role in many cellular functions such as
apoptosis and inflammation. During the past decade emerging clinical data have shown that …

Increases in calorie consumption and sedentary lifestyles are fuelling a global pandemic of
cardiometabolic diseases, including coronary artery disease, diabetes mellitus …

Objective—Ceramides are molecular lipids implicated in apoptosis, inflammation, obesity,
and insulin resistance. An earlier study reported that ceramides were associated with fatal …