N6-methyladenosine methylation modification patterns reveal immune profiling in pancreatic adenocarcinoma

H Xu, L Yin, Q Xu, J Xiang, R Xu - Cancer cell international, 2022 - Springer
Background Several studies have revealed that N6-methyladenosine (m6A) regulation is
involved in various biological processes and cancer progression. Nevertheless, the potential …

Analysis of N6-methyladenosine modification patterns and tumor immune microenvironment in pancreatic adenocarcinoma

Y Liu, G Li, Y Yang, Z Lu, T Wang, X Wang… - Frontiers in Genetics, 2022 - frontiersin.org
Background: Pancreatic adenocarcinoma (PAAD) is a rare cancer with a poor prognosis. N6-
methyladenosine (m6A) is the most common mRNA modification. However, little is known …

m6A Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization in Pancreatic Cancer

M Sun, M Xie, T Zhang, Y Wang, W Huang… - Frontiers in …, 2021 - frontiersin.org
Recent studies have shown that RNA N6-methyladenosine (m6A) modification plays an
important part in tumorigenesis and immune-related biological processes. However, the …

Characterization of Modification Patterns, Biological Function, Clinical Implication, and Immune Microenvironment Association of m6A Regulators in Pancreatic …

K Fang, H Qu, J Wang, D Tang, C Yan, J Ma… - Frontiers in …, 2021 - frontiersin.org
Objective: N6-methyladenosine (m6A) modification may modulate various biological
processes. Nonetheless, clinical implications of m6A modification in pancreatic cancer are …

Identification of a New m6A Regulator‐Related Methylation Signature for Predicting the Prognosis and Immune Microenvironment of Patients with Pancreatic Cancer

T Zou, D Shi, W Wang, G Chen, X Zhang… - Mediators of …, 2023 - Wiley Online Library
Pancreatic cancer (PC) is a malignant tumor of the digestive system that has a bad
prognosis. N6‐methyladenosine (m6A) is involved in a wide variety of biological activities …

The role of m6A-related genes in the prognosis and immune microenvironment of pancreatic adenocarcinoma

R Tang, Y Zhang, C Liang, J Xu, Q Meng, J Hua, J Liu… - PeerJ, 2020 - peerj.com
Background Pancreatic adenocarcinoma (PAAD) is among the most lethal diseases and has
a dismal prognosis; however, efficient treatment is currently limited. Several studies have …

[HTML][HTML] The expression of m6A regulators correlated with the immune microenvironment plays an important role in the prognosis of pancreatic ductal adenocarcinoma

Y Yao, L Luo, G Xiang, J Xiong, N Ke, C Tan… - Gland …, 2022 - ncbi.nlm.nih.gov
Background The relationship between N6-methyladenosine (m 6 A) RNA methylation
regulators and the tumor immune microenvironment has been extensively studied …

m6A regulator-mediated methylation modification highlights immune infiltration patterns for predicting risk in hepatocellular carcinoma

D Zhou, Y Wang, W Wei, W Zhou, J Gu, Y Kong… - Journal of Cancer …, 2023 - Springer
Background Increasing studies have demonstrated the biological function of RNA N6-
methyladenosine (m6A) modifications in tumorigenesis. However, the potential role of m6A …

[HTML][HTML] m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in hepatocellular carcinoma

X Huang, Z Qiu, L Li, B Chen, P Huang - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Background: There is increasing evidence of the epigenetic regulation of the immune
response in cancer. However, the specific functions and mechanisms of RNA N6 …

[HTML][HTML] Comprehensive analysis of m6A RNA methylation regulators and the immune microenvironment to aid immunotherapy in pancreatic cancer

Y Guo, R Wang, J Li, Y Song, J Min, T Zhao… - Frontiers in …, 2021 - frontiersin.org
Pancreatic cancer (PAAD) is one of the most malignant cancers and immune
microenvironment has been proved to be involved in pathogenesis of PAAD. m6A …