Natriuretic peptides (NPs) counter the effects of volume overload or adrenergic activation of
the cardiovascular system. They are able to induce arterial vasodilatations, natriuresis and …

Natriuretic peptides (NPs) are the principal expression products of the endocrine function of
the heart. They exert several beneficial effects, mostly mediated through guanylate cyclase …

Natriuretic peptides (NP) are widely recognized as key regulators of blood pressure, water
and salt homeostasis. In addition, they play a critical role in physiological cardiac growth and …

It is now well established that the heart and vascular endothelium are endocrine glands that
synthesize and release natriuretic and vasoactive peptides. Specifically, the cardiac myocyte …

Natriuretic peptides, which are activated in heart failure, play an important cardioprotective
role. The most notable of the cardioprotective natriuretic peptides are atrial natriuretic …

Following the initial discovery of a natriuretic and diuretic peptide factor present in atrial
myocardial tissue homogenates, subsequent elucidation of the natriuretic peptide (NP) …

The current standard treatment of chronic heart failure (HF) is based on clinical judgment,
with the goal of achieving the maximally tolerated therapeutic program. The complexity of …

Natriuretic peptides (atrial natriuretic peptide, brain natriuretic peptide and C-type natriuretic
peptide) are cardiac and vascular peptides with vasodilatory, diuretic, natriuretic, anti …

Heart failure is a major clinical problem affecting 64 million people worldwide with a 5-year
mortality rate of around 50%. Patients present to the emergency department with inability to …

The last two centuries have witnessed countless discoveries in the field of medicine that
found their roots in the up growing development of technology as well as in the visionary …